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CompletedNCT06573502Updated Dec 12, 2025

Platelet Rich Plasma Combined With Platelet Rich Fibrin in Management of Temporomandibular Joint Osteoarthritis

An interventional study of Prp with prf or prp or prf in Osteoarthritis, sponsored by Aliaa Babekir Ahmed Mohamed. Completed at 1 site in Egypt. Per ClinicalTrials.gov, last updated 2025-12-12.

Sponsored by Aliaa Babekir Ahmed Mohamed · Not applicable, Interventional, and Treatment

Phase
Not applicable
Study type
Interventional
Enrollment
42
Allocation
Randomized
Sex
All
01

Study summary

Studying effectiveness of prp with prf comparing with prp or prf for mangement of tmj osteoarthritis as result in pain and mandibular movement in adult pt

Read the detailed description

45 pt assigned for the study , divided in to three gruops to comparing new combination of prp with prf in management of TMJ OA

02

Conditions studied

  • Osteoarthritis

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03

In context

Osteoarthritis

4,398 studies on the registry are indexed under Osteoarthritis; 582 are open to participants now.

This study's enrollment of 42 is below the median of 70 across 3,440 interventional studies indexed under Osteoarthritis.

Browse Osteoarthritis studies →

Lead sponsor

This is the only study on the registry with Aliaa Babekir Ahmed Mohamed as lead sponsor.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

Adult pt with OA

Exclusion criteria

Exclusion Criteria:

Medicaly compromised

05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Quadruple (Participant, Care provider, Investigator, Outcomes assessor)
Enrollment
42 participants (actual)

Study arms

  • Experimental
    prp with prf group

    Pt will recievd prp with prf

    Combination Product: Prp with prf or prp or prf

  • Active comparator
    prp group

    Pt will recieve prp only

    Combination Product: Prp with prf or prp or prf

  • Experimental
    prf group

    Pt will recieve prf only

    Combination Product: Prp with prf or prp or prf

Interventions

  • Combination productPrp with prf or prp or prf

    Combination

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What researchers measure

Primary outcomes

  1. Pain severty

    Visual analog scale measure for pain most sever pain take 10 minimum pain take 0

    Time frame: 6 months

Secondary outcomes

  1. Maximum mouth opening

    Measured with calipar

    Time frame: 6 months

07

Study locations

1 site
  • Cairo university
    Cairo, Egypt
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Dec 12, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT06573502
Lead sponsor
Aliaa Babekir Ahmed Mohamed
Responsible party
Aliaa Babekir Ahmed Mohamed (principal investigator, Cairo University) — Sponsor-investigator
First posted
Aug 27, 2024
Start date
Mar 29, 2025
Primary completion
Sep 29, 2025
Completion
Nov 16, 2025
Last update
Dec 12, 2025

Study contacts

Hassan Ab Ghany, Prof
study director · Cairo University

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Dec 2025. You cannot join it, but the record below documents what was studied.

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