An observational study in Central Sensitisation, Postoperative Pain and Arthritis, sponsored by Istanbul University. Not yet recruiting. Open to participants aged 60 Years to 75 Years. Per ClinicalTrials.gov, last updated 2024-08-15.
Sponsored by Istanbul University · Observational
The study is a prospective observational study designed to determine the effects of central sensitization on pain and functional status of patients before and after total knee joint replacement surgery.
The aim of this study is to evaluate whether there is a difference in preoperative and postoperative pain and functional status between patients with and without central sensitization with knee osteoarthritis.
When the literature was reviewed, it was seen that central sensitization was one of the important mechanisms that caused pain in knee osteoarthritis, and it was determined that this had negative consequences in terms of postoperative pain and improvement in functional status. In this study, the effect of central sensitization on the results will be investigated by evaluating pain and functional status before and after knee total joint prosthesis in two groups of knee osteoarthritis patients, with and without central sensitization, and by comparing the groups.
5,093 studies on the registry are indexed under Pain, Postoperative; 1,140 are open to participants now.
This study's planned enrollment of 80 is below the median of 102 across 608 observational studies indexed under Pain, Postoperative.
Browse Pain, Postoperative studies →Istanbul University is the lead sponsor of 496 studies on the registry; 79 are open to participants now.
Of its 5 completed or terminated interventional studies of FDA-regulated products, 1 (20%) have results posted.
Counted across the registry records on this site, refreshed daily.
The study population consists of patients who were planned to have total knee arthroplasty for primary knee osteoarthritis
Exclusion Criteria:
Patients with central sensitization
Procedure: Total knee arthroplasty
Patients without central sensitization
Procedure: Total knee arthroplasty
Patients already admitted for total knee arthroplasty for knee osteoarthritis will have the procedure as planned
Knee pain
Knee pain will be assessed with numerical rating scale, where the patients rate their pain on a scale from 0 to 10 where 0 means no pain and 10 means the most severe pain they can imagine.
Time frame: Preoperative, 1 month postoperative and 3 months postoperative
Functional Status
Functionality of the patients will be assessed with WOMAC (Western Ontario and McMaster Universities Osteoarthritis Index). Responses are typically rated on a scale from 0 (none) to 4 (extreme). Higher scores indicate greater impairment.
Time frame: Preoperative, 1 month postoperative and 3 months postoperative
No study locations are listed for this record.
Plan to share: No
No publications or documents are linked to this record.
This study is not yet recruiting, as verified in Aug 2024. You cannot join it, but the record below documents what was studied.
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Istanbul University