A Phase 1 interventional study of Bromelain gel and chlorhexidine gel in Periodontal Pocket, sponsored by Krishnadevaraya College of Dental Sciences & Hospital. Recruiting at 1 site in India. Open to participants aged 30 Years to 50 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2025-01-13.
Sponsored by Krishnadevaraya College of Dental Sciences & Hospital · Phase 1, Interventional, and Treatment
The current study is a prospective randomised study Evaluation of 2%Bromelain Gel With 0.2%Chlorhexidine Gel as Subgingival Local Drug Delivery Following Scaling and Root Planing in Stage II/III and Grade B Periodontitis
36 sites with periodontal pocket depth measuring 4-6mm were selected. The sites selected were divided into
periodontal pack was placed and patient was recalled at 1week,4th week and 12th week
130 studies on the registry are indexed under Periodontal Pocket; 35 are open to participants now.
This study's planned enrollment of 36 is above the median of 30 across 113 interventional studies indexed under Periodontal Pocket.
Browse Periodontal Pocket studies →Krishnadevaraya College of Dental Sciences & Hospital is the lead sponsor of 51 studies on the registry; 13 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Patients having ≥20 teeth.
-.Patients with radiographic evidence of bone loss in atleast two teeth.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
control group is treated with SRP alone
Procedure: SRP
test group is treated with bromelain gel
Drug: Bromelain gel
test group is treated with chlorhexidine gel
Drug: chlorhexidine gel
bromelain gel is prepared from bromelain capsules in laboratory
chlorhexidine gel is prepared from mouth wash
Scaling and root planing was done with ultra sonic and hand scaling
Probing pocket Depth (PPD)
measured using a UNC-15 probe (university of North Carolina-15 periodontal probe- Hu-Friedy, Chicago, IL, USA
Time frame: 3 months
Relative attachment level (RAL)
(university of North Carolina-15 periodontal probe- Hu-Friedy, Chicago, IL, USA)
Time frame: 3 months
Plaque Index
measured on the tooth surface using a probe
Time frame: 3 months
Gingival index
measured on the tooth surface using a probe
Time frame: 3 month
Modified Sulcus Bleeding Index
measured on the tooth surface using a probe
Time frame: 3 months
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Studies of the drug tested here: Bromelains
Krishnadevaraya College of Dental Sciences & Hospital