An observational study in Age Problem, Disability and Dementia, sponsored by Xuanwu Hospital, Beijing. Recruiting at 1 site in China. Open to participants aged 60 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2024-06-25.
Sponsored by Xuanwu Hospital, Beijing · Observational
This is a community-based prospective cohort study in China. The study has been initialized in 2024 and included older residents. The goal of this observational study is to explore the risk factors related to disability and dementia in the elderly Chinese community population, and develop a risk prediction model for disability and dementia.
This is a community-based prospective cohort study in China. Individuals who were aged 60 years or older, had lived in the communities for more than 1 year, and had signed the informed consent form were enrolled in the present study. The study has been initiated in 2024 and aimed to explore the risk factors related to disability and dementia in the elderly Chinese population, and develop a risk prediction model for disability and dementia. This work consists of three steps as follows. First, by integrating the data of the elderly cohort of 4 communities in Beijing, Shenzhen, Haikou and Hangzhou, we plan to establish a Chinese elderly database. Second, to explore the risk factors of disability and dementia in elderly Chinese. Third, to construct risk prediction models of disability and dementia in Chinese elderly.
2,172 studies on the registry are indexed under Dementia; 540 are open to participants now.
This study's planned enrollment of 6,780 is above the median of 250 across 482 observational studies indexed under Dementia.
Browse Dementia studies →Xuanwu Hospital, Beijing is the lead sponsor of 346 studies on the registry; 217 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Community residents aged 60 years or older in China
Exclusion Criteria:
All subjects
Other: No intervention
No intervention
The prevalence and incidence of functional disability using a population-based survey
Functional disability was measured by Activities of Daily Living, cognitive function (Mini-Mental State Examination) and movement disorder（Short Physical Performance Battery) collected by questionnaires.The minimum value of the Activities of Daily Living is 0, and the maximum value is 100, the higher the score, the better the outcome.The minimum value of the Mini-Mental State Examination is 0, and the maximum value is 30, the higher the score, the better the outcome.The minimum value of the Short Physical Performance Battery is 0, and the maximum value is 12, the higher the score, the better the outcome.
Time frame: An average of 1 to 2 years
The prevalence and incidence of mild cognitive impairment using a population-based survey
Mild cognitive impairment was measured using Mini-Mental State Examination collected by questionnaire.The minimum value of the Mini-Mental State Examination is 0, and the maximum value is 30, the higher the score, the better the outcome.
Time frame: An average of 1 to 2 years
The prevalence and incidence of dementia using a population-based survey
Dementia was determined by diagnosis of hospitalization or diagnosis of death or Clinical Dementia Rating scale. The minimum value of the Clinical Dementia Rating is 0, and the maximum value is 3, the higher the score, the worse the outcome.
Time frame: An average of 1 to 2 years
The conversion rate of normal to mild cognitive impairment
Percentage of enrolled population that convert from normal to mild cognitive impairment
Time frame: An average of 1 to 2 years
The conversion rate of mild cognitive impairment to dementia
Percentage of enrolled population that convert from mild cognitive impairment to dementia
Time frame: An average of 1 to 2 years
The prevalence and incidence of movement disorder using a population-based survey
Movement disorder was measured using Short Physical Performance Battery collected by questionnaire.The minimum value of the Short Physical Performance Battery is 0, and the maximum value is 12, the higher the score, the better the outcome.
Time frame: An average of 1 to 2 years
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Xuanwu Hospital, Beijing