CClinicalTrials.gg
CompletedNCT06420791Updated May 20, 2024

The Dual Impact of Cirrhosis on Transplantation for Hepatocellular Carcinoma:a Two-center Retrospective Cohort Study in China

An observational study in Hepatocellular Carcinoma and Cirrhosis, sponsored by Xiao Xu. Completed at 1 site in China. Per ClinicalTrials.gov, last updated 2024-05-20.

Sponsored by Xiao Xu · Observational

Study type
Observational
Model
Cohort
Time perspective
Retrospective
Enrollment
1
Sex
All
01

Study summary

Background: This study aims to investigate the correlation between cirrhosis and hepatocellular carcinoma (HCC) recurrence after Liver Transplantation.

Methods: The study retrospectively collected data enrolled from 519 HCC patients who underwent liver transplantation from two center(the First Affiliated Hospital, Zhejiang University School of Medicine and Shulan (Hangzhou) Hospital, January 2015 to December 2020), Based on important variables, 1:3 propensity score matching (PSM) were performed respectively.

02

Conditions studied

03

In context

Carcinoma

6,741 studies on the registry are indexed under Carcinoma; 1,161 are open to participants now.

This study's enrollment of 1 is below the median of 149 across 1,175 observational studies indexed under Carcinoma.

Browse Carcinoma studies →

Lead sponsor

Xiao Xu is the lead sponsor of 4 studies on the registry; none are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Previously registered liver transplant recipients

Inclusion criteria

The patients undergoing liver transplantation for HCC from January 2015 to December 2020.

Exclusion criteria

Exclusion Criteria:

Re-transplantation or combined liver-kidney transplantation; incomplete laboratory or clinical data; death within 90 days.

05

Study design

Observational model
Cohort
Time perspective
Retrospective
Enrollment
1 participant (actual)
Patient registry
No
06

What researchers measure

Primary outcomes

  1. The overall survival rate was evaluated by follow-up investigation and outpatient review

    Time frame: 2-5 years

Secondary outcomes

  1. The tumor-free survival rate was evaluated by follow-up investigation and outpatient review

    Time frame: 2-5 years

07

Study locations

1 site
  • Zhejiang University school of Medicine
    Hangzhou, Zhejiang 310000, China
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on May 20, 2024, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT06420791
Lead sponsor
Xiao Xu
Responsible party
Xiao Xu (Principal Investigator, Clinical Professor,PHD,MD, Zhejiang University) — Sponsor-investigator
First posted
May 20, 2024
Start date
Feb 28, 2024
Primary completion
May 3, 2024
Completion
May 6, 2024
Last update
May 20, 2024

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in May 2024. You cannot join it, but the record below documents what was studied.

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Sign in to follow

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Start the discussion