An interventional study of subgingival mechanotherapy with perioscopy and classical subgingival mechanotherapy in Periodontitis, sponsored by Medical University of Warsaw. Completed at 1 site in Poland. Open to participants aged 20 Years to 60 Years. Per ClinicalTrials.gov, last updated 2026-07-24.
Sponsored by Medical University of Warsaw · Not applicable, Interventional, and Treatment
The study aims to comparatively assess clinical parameters, biochemical and microbiological parameters after treatment of periodontitis using subgingival mechanotherapy traditional and subgingival mechanotherapy using a perioscope.
Non-surgical treatment is the basic form of disease treatment periodontitis. Its first stage is the mechanical removal of dental plaque along with the control of risk factors. Subgingival mechanotherapy, also known as scaling and root planing (SRP) is the next stage, aimed at the subgingival area. Perioscopy makes possible direct real-time visualization of the root surface during the procedure. The research results published so far indicate improvement or no significant differences clinical parameters after SRP procedure using a perioscope vs traditional subgingival instrumentation. The aim of this study is to indicate, or not, clinical, biochemical (level of pro-inflammatory cytokines) and microbiological (A. actinomycetemcomitans, P. gingivalis, T. denticola) differences after periodontitis treatment using the traditional method vs. using a perioscope.
1,635 studies on the registry are indexed under Periodontitis; 327 are open to participants now.
This study's enrollment of 26 is below the median of 45 across 1,191 interventional studies indexed under Periodontitis.
Browse Periodontitis studies →Medical University of Warsaw is the lead sponsor of 316 studies on the registry; 87 are open to participants now.
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Exclusion Criteria:
Scaling and root planing using ultrasonic scaler and curettes, under the control of a perioscope, enabling real-time, magnified imaging of the root surface.
Device: subgingival mechanotherapy with perioscopy
Scaling and root planing using ultrasonic scaler and curettes.
Device: classical subgingival mechanotherapy
Subgingival mechanotherapy using a machine scaler, curettes and a perioscope
Subgingival mechanotherapy using a machine scaler and curettes
Probing pocket depth (PPD)
Distance from the gingival margin to the bottom of the gingival sulcus
Time frame: 0 (before), 3 and 6 months after SRP
Clinical attachment level (CAL)
Distance from the cementoenamel junction to the bottom of the gingival sulcus
Time frame: 0 (before), 3 and 6 months after SRP
Bleeding on probing (BoP)
Percentage of sites with bleeding provoked by applying a probe to the bottom of a sulcus/pocket.
Time frame: 0 (before), 3 and 6 months after SRP
Plaque index (PI)
Percentage of sites with plaque
Time frame: 0 (before), 3 and 6 months after SRP
Width of keratinized tissue (KTW)
Distance between the most apical point of gingival margin and the mucogingival junction
Time frame: 0 (before), 3 and 6 months after SRP
Gingival thickness (GT)
Thickness of the gingiva measured 2 mm apical to the gingival margin
Time frame: 0 (before), 3 and 6 months after SRP
Subgingival plaque pathogens (Aa, Pg, Td) levels
Levels of periodontal pathogens (Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, Treponema denticola) measured with real-time polymerase chain reaction (RT-PCR) test; data presented as number of bacteria of these species and percentage of total bacteria found in a sample; sample taken from the deepest pocket on each side.
Time frame: 0 (before) and 6 months after SRP
Gingival crevicular fluid levels of cytokines
Levels of (IL - interleukin) IL-1β, IL-6, IL-8, IL-10 and interferon-gamma in gingival crevicular fluid presented as pg/ml; sample taken from the deepest pocket on each side.
Time frame: 0 (before), 3 and 6 months after SRP
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This study is completed, as verified in Jun 2023. You cannot join it, but the record below documents what was studied.
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Medical University of Warsaw