An observational study in Primary Dysmenorrhea, sponsored by Cairo University. Completed at 1 site in Egypt. Open to female participants aged 17 Years to 25 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2025-01-29.
Sponsored by Cairo University · Observational
This study will be conducted to determine the correlation between the levels of serum progesterone and Menstrual Symptoms In Young Females with primary dysmenorrhea.
One hundred adult females with primary dysmenorrhea will participate in this study. They will be recruited from the Gynaecological outpatient clinic, Kasr El Ainy University Hospital, Cairo, Egypt Many studies reported that primary dysmenorrhea was the result of increased prostaglandin, especially prostaglandin F2α (PGF2α) and prostaglandin E2 (PGE2) which produced the effect through the cyclooxygenase pathway, and further led to uterine ischemia hypoxia. Nevertheless the relationship between the serum progesterone level and menstrual symptoms was not completely clear. Hence, this study will investigate the association between the serum progesterone level and menstrual symptoms in young females with primaryf dysmenorrhea.
398 studies on the registry are indexed under Dysmenorrhea; 96 are open to participants now.
This study's enrollment of 100 is below the median of 123 across 56 observational studies indexed under Dysmenorrhea.
Browse Dysmenorrhea studies →Cairo University is the lead sponsor of 4,780 studies on the registry; 1,427 are open to participants now.
Of its 36 completed or terminated interventional studies of FDA-regulated products, 5 (14%) have results posted.
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One hundred girls with dysmenorrhoea. Menarche at least 3 years ago. All females should be regular menstrual cycles.
Exclusion Criteria:
Any participant will be excluded from the study if they have:
One hundred young females with primary dysmenorrhea will participate in this study. They will be recruited from the Gynecological outpatient clinic, Kasr El Ainy University Hospital, Cairo, Egypt. All females should have regular menstrual cycles. Taking blood samples of 3 ml through the cubital vein to examine the levels of serum progesterone will be carried out on the 21st day of menstruation, while to assess the pain intensity of primary dysmenorrhea using the Visual Analogue Scale (VAS) and physical and psychological symptoms associated with dysmenorrhea will be assessed by menstrual symptoms questionnaire .
Serum progesterone level
Blood samples will be taken by physician for each girl, and will send to laboratory center to measure the progesterone level in the blood. The normal serum progesterone level at 21st day is 4-20 ng
Time frame: 1 month
Pain intensity
It will be measured by Visual analogue scale. It is 10 cm line with values ranging from 0 to 10. 0 indicates no pain nd 10 indicates the worst pain.
Time frame: 1 month
Physical and psychological menstrual symptoms
It will be measured by menstrual symptoms questionnaire. It is 25 items split into two categories which used to assess the physical and psychological symptoms associated with dysmenorrhea. The score on each item ranged from 1 (never) to 5 (always) with a higher composite score indicating more symptoms
Time frame: 1 month
Correlation between serum progesterone level and pain
The correlation between serum progesterone level and pain intensity measured by the VAS will be conducted
Time frame: 1 month
Correlation between serum progesterone level and menstrual symptoms
The correlation between serum progesterone level and menstrual symptoms measured by the menstrual symptom questionnaire will be conducted
Time frame: 1 month
Plan to share: Undecided
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This study is completed, as verified in Apr 2024. You cannot join it, but the record below documents what was studied.
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Cairo University