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CompletedNCT06306105Updated Sep 19, 2024

Assessment of Anti-aging Efficacy of Marine Collagen Peptides

An interventional study of Marine Collagen Peptides and placebo drink in Skin Condition, Hair Fragility and Nails, Ingrown, sponsored by TCI Co., Ltd.. Completed at 1 site in Taiwan. Open to participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2024-09-19.

Sponsored by TCI Co., Ltd. · Not applicable, Interventional, and Prevention

Phase
Not applicable
Study type
Interventional
Enrollment
60
Allocation
Randomized
Ages
18 Years and older
Sex
All
01

Study summary

To assess the anti-aging efficacy of Marine Collagen Peptides on skin, hair and finger nails for human

02

Conditions studied

  • Skin Condition
  • Hair Fragility
  • Nails, Ingrown

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Keywords

  • fish collagen
03

In context

Skin Diseases

544 studies on the registry are indexed under Skin Diseases; 93 are open to participants now.

This study's enrollment of 60 is close to the median of 60 across 379 interventional studies indexed under Skin Diseases.

Browse Skin Diseases studies →

Lead sponsor

TCI Co., Ltd. is the lead sponsor of 61 studies on the registry; 7 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
Yes

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Healthy adults aged above 18 years old

Exclusion criteria

Exclusion Criteria:

  • Subjects who are not volunteers
  • Subjects who have been diagnosed with dermatitis, cirrhosis, and chronic kidney failure
  • Subjects who have known cosmetic, drug or food allergies.
  • Patients are taking medicine for chronic diseases
  • Subjects receiving treatments for scalp, hair transplant, and other scalp medical care in past 12 weeks.
  • Subjects getting a manicure and perm in past 12 weeks.
  • Female who is pregnant or nursing or planning to become pregnant during the course of the study.
  • Subjects receiving facial laser therapy, chemical peeling or UV overexposure (> 3 hr/week) in the past 12 weeks.
  • Students who are currently taking courses taught by the principal investigator of this trial.
  • Subjects are not willing to reveal the results of pictures after taking the product
  • Vegetarian.
05

Study design

Phase
Not applicable
Primary purpose
Prevention
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Double (Participant, Investigator)
Enrollment
60 participants (actual)

Study arms

  • Placebo comparator
    placebo drink

    Dietary Supplement: placebo drink

  • Experimental
    Marine Collagen Peptides drinks

    Dietary Supplement: Marine Collagen Peptides

Interventions

  • Dietary supplementMarine Collagen Peptides

    consume 1 bottle per day

    Also known as: Coral club Promarine Collagen Tripeptides

  • Dietary supplementplacebo drink

    consume 1 bottle per day

06

What researchers measure

Primary outcomes

  1. The change of skin hydation

    Corneometer® CM825 (CK, Germany) was utilized to measure skin surface hydation. Units: arbitrary Corneometer® units 0-120.

    Time frame: Change from Baseline skin skin hydation at 12 weeks

  2. The change of skin wrinkles

    VISIA Complexion Analysis was utilized to measure skin wrinkles. Units: the amount of detectable wrinkles

    Time frame: Change from Baseline skin wrinkles at 12 weeks

  3. The change of skin elasticity

    Cutometer® MPA580 was utilized to measure skin elasticity. Units: visco-elasticity in %.

    Time frame: Change from Baseline skin elasticity at 12 weeks

  4. The change of skin collagen density

    DermaLab® Series SkinLab Combo was utilized to measure skin collagen density. Units: arbitrary units

    Time frame: Change from Baseline skin collagen density at 12 weeks

  5. The change of hair diameters

    Mitutoyo C/N293-100 was utilized to measure hair diameters. Units: millimeter

    Time frame: Change from Baseline hair diameters at 12 weeks

  6. The change of hair loss amount

    Collect and measure the weight of loss hair. Units: gram

    Time frame: Change from Baseline hair loss amount at 12 weeks

  7. The change of hair roots diameters

    Mitutoyo C/N293-100 was utilized to measure hair roots diameters. Units: millimeter

    Time frame: Change from Baseline hair roots diameters at 12 weeks

  8. The change of hair density

    Soft Plus was utilized to picture and observe hair density.

    Time frame: Change from Baseline hair density at 12 weeks

  9. The change of hair follicle strength

    Pull up the hair of the frontal bone, temporal bone and occipital bone (approximately 60 hairs/area) to assess the number of hair loss in each area. Units: the number of loss hair

    Time frame: Change from Baseline hair follicle strength at 12 weeks

  10. The change of thumbs nail color

    Chroma Meter MM500 was utilized to measure thumbs nail color. Units: L\* index

    Time frame: Change from Baseline thumbs nail color at 12 weeks

  11. The change of nails appearence

    Picture taken was utilized to record and observe nails appearence.

    Time frame: Change from Baseline nails appearence at 12 weeks

  12. The change of nails growth

    Marking the position of middle fingers lunula was utilized to record and observe nails growth. Units: milimeter

    Time frame: Change from Baseline marking position at 12 weeks

  13. The degree of nails fragility

    Iron ruler was utilized to evaluate nails fragility. Picture taken was utilized to record and observe the change of nails fragility.

    Time frame: Change from Baseline nails fragility at 12 weeks

Secondary outcomes

  1. The change of self-assessment skin, hair, and nails condition

    A self-assessment questionnaire was collected and evaluate skin, hair, and nails condition

    Time frame: Change from Baseline skin, hair, and nails condition at 12 weeks

07

Study locations

1 site
  • Chia Nan University of Pharmacy & Science
    Pingtung City, 928, Taiwan
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Sep 19, 2024, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT06306105
Lead sponsor
TCI Co., Ltd.
Responsible party
Sponsor
First posted
Mar 12, 2024
Start date
Mar 4, 2024
Primary completion
Jun 30, 2024
Completion
Aug 31, 2024
Last update
Sep 19, 2024

Study contacts

Chia-Hua Liang, Ph.D.
principal investigator · Chia Nan University of Pharmacy & Science

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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This study is completed, as verified in Sep 2024. You cannot join it, but the record below documents what was studied.

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