An observational study in Skin Diseases, Photoaging and Skin Hydration, sponsored by IAS Skin Care. Recruiting at 1 site in United States. Open to female participants aged 25 Years to 65 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-10-13.
Sponsored by IAS Skin Care · Observational
his observational study examines whether time spent driving is associated with differences in skin hydration between the left and right cheeks in female drivers residing in Florida. In left-hand-drive vehicles, the driver's left cheek is chronically exposed to ultraviolet A (UVA) radiation through the unshaded side window during every daytime driving episode. A prior study by IAS Skin Care (NCT07564869, n=30) found that the left cheek was less hydrated than the right cheek in 60% of participants, suggesting a possible effect of driving-related UVA exposure on facial skin hydration asymmetry.
Eighty female drivers aged 25-65 years residing in Florida will be enrolled. At a single visit, skin hydration will be measured at three facial zones (left cheek, right cheek, and forehead as a symmetrical control zone) using the BT-Analyze bioimpedance device. Participants will complete a structured questionnaire on driving habits, sun protection practices, and skin history. The primary outcome is the Hydration Asymmetry Index (HAI = right cheek minus left cheek BT-Analyze score). Associations between driving time, cumulative driving exposure, window tinting, sunscreen use, and HAI will be examined using Spearman correlation, Mann-Whitney U tests, and multiple linear regression.
496 studies on the registry are indexed under Skin Diseases; 77 are open to participants now.
This study's planned enrollment of 80 is below the median of 165 across 101 observational studies indexed under Skin Diseases.
Browse Skin Diseases studies →IAS Skin Care is the lead sponsor of 2 studies on the registry; 1 is open to participants now.
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Convenience sample of female drivers aged 25-65 years residing in Florida, recruited from an esthetics practice client base and referral networks in the Orlando metropolitan area.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Female drivers aged 25-65 years residing in Florida for at least two years, driving at least 3 days per week, without window tinting on the driver-side window.
Other: BT-Analyze bioimpedance skin hydration measurement
Non-invasive skin hydration measurement at three facial zones (right cheek, left cheek, forehead) using the BT-Analyze bioimpedance device. Three measurements per zone. Single visit.
Hydration Asymmetry Index (HAI)
Difference in mean BT-Analyze bioimpedance scores between the right and left cheeks (HAI = right cheek mean minus left cheek mean). A positive value indicates lower hydration on the left cheek relative to the right.
Time frame: Single visit (Day 1)
Correlation between cumulative driving exposure and HAI
Spearman correlation between cumulative driving exposure index (years of driving × hours per week) and the Hydration Asymmetry Index.
Time frame: Single visit (Day 1)
HAI by window tinting status
Comparison of Hydration Asymmetry Index between participants with tinted versus untinted driver-side windows, assessed by Mann-Whitney U test.
Time frame: Single visit (Day 1)
HAI by sunscreen application habit
Comparison of Hydration Asymmetry Index between participants who regularly apply sunscreen to the left side of the face before driving and those who do not, assessed by Mann-Whitney U test.
Time frame: Single visit (Day 1)
Forehead hydration as symmetry reference
Forehead BT-Analyze score used as a bilateral symmetry reference zone to confirm that observed cheek asymmetry is directional and not attributable to general hydration differences.
Time frame: Single visit (Day 1)
Plan to share: No
No publications or documents are linked to this record.
From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
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IAS Skin Care