An interventional study of Oral fluid and IV fluid in Osteoarthritis, Knee, Total Knee Arthroplasty and Oral Fluid Replacement, sponsored by Thammasat University Hospital. Recruiting at 1 site in Thailand. Open to participants aged 40 Years to 85 Years. Per ClinicalTrials.gov, last updated 2024-03-04.
Sponsored by Thammasat University Hospital · Not applicable, Interventional, and Treatment
The goal of this study is to compared efficacy of oral fluid and intravenous fluid after primary unilateral total knee arthroplasty.
The main question it aims to answer is:
Does oral fluid replacement after primary unilateral total knee arthroplasty provide a patient recover faster than intravenous fluids replacement?
3,302 studies on the registry are indexed under Osteoarthritis, Knee; 608 are open to participants now.
This study's planned enrollment of 130 is above the median of 70 across 2,731 interventional studies indexed under Osteoarthritis, Knee.
Browse Osteoarthritis, Knee studies →Thammasat University Hospital is the lead sponsor of 16 studies on the registry; 7 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
* NPO (8hr for food, 2hr for water) * Intraoperative IV fluid at least 1 liter * Post operative (Off IV fluid, allow oral fluid as protocol at least 24hr)
Dietary Supplement: Oral fluid
* NPO (8hr for food, 2hr for water) * Intraoperative IV fluid at least 1 liter * Post operative (IV fluid as protocol at least 24hr, allow oral fluid as usual)
Dietary Supplement: IV fluid
Postoperation * Off IV fluid immediately postoperative * Allow patients drink oral fluid as protocol for 24hr
Postoperation * IV fluid replacement as protocol for 24hr * Allow patients drink oral fluid as usual
Time to stand and walk
Stand and walk with walker
Time frame: Postoperative day 1
Time up and go
Record time since stand up and walk 3 meters, or 10 feet away, on the floor
Time frame: 24 and 48 hours
Incidence of oliguria
Urine output \< 0.5ml/kg/hr
Time frame: Postoperative day 1,2
Incidence of nausea/vomiting
record symptom of nausea and vomiting
Time frame: Postoperative day 1,2
Urine specific gravity
Urine specific gravity every 4 hours
Time frame: Postoperative day 1
the levels of certain electrolytes
Blood chemistry
Time frame: Postoperative day 1,2
the levels of creatinine
Blood chemistry
Time frame: Postoperative day 1,2
the levels of blood urea nitrogen (BUN).
Blood chemistry
Time frame: Postoperative day 1,2
Complications
Pulmonary edema, heart failure, acute kidney injury
Time frame: Until postoperative 3months
Plan to share: No
Eligibility is decided by the study team. Share this record with your doctor or contact the team directly.
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Thammasat University Hospital