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RecruitingNCT06245187GWTG-AFUpdated Jan 29, 2025

Get With the Guidelines Atrial Fibrillation Registry

An observational study in Atrial Fibrillation and Atrial Flutter, sponsored by American Heart Association. Recruiting at 1 site in United States. Open to participants aged 18 Years to 125 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2025-01-29.

Sponsored by American Heart Association · Observational

Study type
Observational
Model
Cohort
Time perspective
Other
Enrollment
17,198
Ages
18 Years to 125 Years
Sex
All
01

Study summary

Get With The Guidelines-Atrial Fibrillation is designed to assist hospital care teams in consistently providing the latest evidence-based treatment for their AFib patients. At the same time, it offers a means of monitoring the quality of AFib care in U.S. hospitals and building a database for continued research and further quality improvement.

Read the detailed description

Get With The Guidelines-Atrial Fibrillation was initiated in 2013 with over 88 U.S. hospitals participating is designed to assist hospital care teams in consistently providing the latest evidence-based treatment for their AFib patients. At the same time, it offers a means of monitoring the quality of AFib care in U.S. hospitals and building a database for continued research and further quality improvement.

Achievement measures tracked through Get With The Guidelines-Atrial Fibrillation:

  1. ACEI/ARB at discharge for LVSD
  2. Assessment of thromboembolic risk factors
  3. Beta Blocker at discharge
  4. Discharged on FDA-approved anticoagulation therapy
  5. PT/INR planned follow-up
  6. Statin at discharge in AF patients with CAD, CVA/TIA or PVD.

Quality measures tracked through Get With The Guidelines-Atrial Fibrillation:

  1. Aldosterone antagonist at discharge
  2. Atrial fibrillation patient education
  3. Anticoagulation therapy education
  4. CHA2DS2-VASC reported
  5. Discharge heart rate \<110bpm
  6. Smoking cessation
  7. Warfarin at discharge for valvular atrial fibrillation

Additional measures collected by Get With The Guidelines-Atrial Fibrillation can be viewed at: http://www.heart.org/idc/groups/heart-public/@private/@wcm/@hcm/@gwtg/documents/downloadable/ucm_451183.pdf

02

Conditions studied

  • Atrial Fibrillation
  • Atrial Flutter
03

In context

Atrial Fibrillation

4,009 studies on the registry are indexed under Atrial Fibrillation; 961 are open to participants now.

This study's planned enrollment of 17,198 is above the median of 300 across 1,400 observational studies indexed under Atrial Fibrillation.

Browse Atrial Fibrillation studies →

Lead sponsor

American Heart Association is the lead sponsor of 13 studies on the registry; 6 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 125 Years
Sexes eligible
All
Accepts healthy volunteers
Yes
Sampling method
Probability sample

Study population

The study population is patients with the diagnosis of nonvalvular Atrial Fibrillation or Atrial Flutter.

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Patients hospitalized with nonvalvular Atrial Fibrillation or Atrial Flutter

Exclusion criteria

Exclusion Criteria:

  • Patients who do not have nonvalvular Atrial Fibrillation or Atrial Flutter
  • Patients under 18 years of age
  • Patients not admitted as inpatients.
  • Patients on comfort care only
  • Patients discharged to hospice.
05

Study design

Observational model
Cohort
Time perspective
Other
Enrollment
17,198 participants (estimated)
Target follow-up
3 Days
Patient registry
Yes

Interventions

  • OtherGWTG Atrial Fibrillation program

    Evidence based recommended therapies and counseling prior to hospital discharge.

06

What researchers measure

Primary outcomes

  1. Cardiac Tamponade and/or Pericardiocentesis Following Ablation

    Percent of patients with cardiac tamponade and/or pericardiocentesis occurring within 30 days following ablation procedure.

    Time frame: 30 days

07

Study locations

1 of 1 sites recruiting
08

References and documents

Publications

  • January CT, Wann LS, Alpert JS, Calkins H, Cigarroa JE, Cleveland JC Jr, Conti JB, Ellinor PT, Ezekowitz MD, Field ME, Murray KT, Sacco RL, Stevenson WG, Tchou PJ, Tracy CM, Yancy CW; American College of Cardiology/American Heart Association Task Force on Practice Guidelines. 2014 AHA/ACC/HRS guideline for the management of patients with atrial fibrillation: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the Heart Rhythm Society. J Am Coll Cardiol. 2014 Dec 2;64(21):e1-76. doi: 10.1016/j.jacc.2014.03.022. Epub 2014 Mar 28. No abstract available. PubMed 24685669 ↗

Individual participant data

Plan to share: Undecided

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jan 29, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT06245187
Lead sponsor
American Heart Association
Responsible party
Sponsor
First posted
Feb 7, 2024
Start date
Jan 2013
Primary completion
Jan 2040 (estimated)
Completion
Jan 2040 (estimated)
Last update
Jan 29, 2025

Study contacts

Amy Bennett, JD
Contact
amy.bennett@heart.org
214-706-2237
Christine Rutan
Contact
Christine.Rutan@heart.org
Javed Butler, MD
principal investigator · American Heart Association

Oversight

Data monitoring committee
Yes
View the source record on ClinicalTrials.gov ↗

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