An observational study in Cognition Disorders in Old Age, Cognitive Decline and Cognitive Impairment, sponsored by University of Macau. Not yet recruiting at 1 site in Macau. Open to participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2024-02-02.
Sponsored by University of Macau · Observational
The current project is dedicated to creating a comprehensive cognitive and neural assessment platform and corresponding norms tailored specifically to the older adults in Macau.
The investigators will establish this assessment platform using a combination of methods, including interviews, surveys, and expert reviews.
Steps include adapting existing assessment methods to the Macau context, developing new cognitive and neural tasks, defining standardized procedures, seeking external expert input, conducting pilot tests, and validation processes, and refining both the platform and its accompanying manual.
3,843 studies on the registry are indexed under Cognitive Dysfunction; 1,100 are open to participants now.
This study's planned enrollment of 300 is above the median of 150 across 950 observational studies indexed under Cognitive Dysfunction.
Browse Cognitive Dysfunction studies →University of Macau is the lead sponsor of 14 studies on the registry; 10 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Adults above 50 years old from the Macau local community.
Exclusion Criteria:
Older adults
Younger adults
Normative Data for the Montreal Cognitive Assessment - Chinese (Hong Kong) version
The MoCA will be administered to derive a normative data set representative of the older adult population in Macau.
Time frame: From February 2024 to January 2026
Normative Data for the Mini-Mental State Examination (MMSE)
The MMSE will be administered to derive a normative data set representative of the older adult population in Macau.
Time frame: From February 2024 to January 2026
Normative Scores for Computerized Neuropsychological Tasks
Neuropsychological tasks will be employed to measure selective attention capacity and processing speed in the study cohort. These tasks will provide quantifiable data on the efficiency and accuracy of cognitive processing. The collective performance on these tasks will be used to establish benchmark values - including means, medians, and ranges - that define the normative standards for these cognitive abilities in the population.
Time frame: From February 2024 to January 2026
Neural Activation Patterns During Cognitive Tasks as Revealed by Functional Magnetic Resonance Imaging (fMRI)
fMRI data will be collected to identify patterns of neural activation associated with cognitive task performance.
Time frame: From February 2024 to January 2026
Cerebral Hemodynamics Assessed Through Functional Near-Infrared Spectroscopy (fNIRS)
fNIRS will be employed to measure cerebral blood flow and oxygenation during cognitive tasks.
Time frame: From February 2024 to January 2026
Electrophysiological Correlates of Cognitive Activity as Measured by Electroencephalography (EEG)
EEG will be utilized to record the electrical activity of the brain during cognitive tasks. Key outcome metrics will include event-related potentials (ERPs) amplitudes and latencies, with mean values and variability measures reported for the cohort.
Time frame: From February 2024 to January 2026
Plan to share: Undecided
No publications or documents are linked to this record.
This study is not yet recruiting, as verified in Jan 2024. You cannot join it, but the record below documents what was studied.
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University of Macau