An observational study in Chronic Venous Insufficiency and Lipedema, sponsored by Hacettepe University. Completed at 1 site in Turkey. Open to female participants aged 18 Years to 75 Years. Per ClinicalTrials.gov, last updated 2024-02-02.
Sponsored by Hacettepe University · Observational
Chronic venous disease (CVD) are common vascular pathology characterized by a wide spectrum of clinical manifestations occurring with symptoms and/or signs that vary in type and severity. The pathophysiological mechanisms of CVD start from the development of venous hypertension, leading to endothelial dysfunction and venous wall dilatation. Lipedema is subcutaneous adipose tissue disorder characterized by enlargement of both lower extremities. Previous studies showed that foot deformities such as pes planus or cavus are at a high prevalence in CVD patients, and the authors indicated that foot disorders are an important risk factor that negatively affects venous disease. To the best of our knowledge, there is only one study investigating plantar arch abnormalities in lipedema patients based on clinical observation. Therefore, the study aimed to investigate plantar foot distribution and foot deformity in patients with CVD and lipedema.
85 studies on the registry are indexed under Lipedema; 32 are open to participants now.
This study's enrollment of 29 is below the median of 90 across 42 observational studies indexed under Lipedema.
Browse Lipedema studies →Hacettepe University is the lead sponsor of 1,007 studies on the registry; 214 are open to participants now.
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The patients were divided into two groups: Patients with only CVD and patients with CVD accompanied lipedema.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Other: Presence of foot deformity, ankle range of motion, foot posture, local tissue water percentage, and foot pressure distribution will be evaluated in patients with chronic venous disease.
Other: Presence of foot deformity, ankle range of motion, foot posture, local tissue water percentage, and foot pressure distribution will be evaluated in patients with chronic venous disease.
Presence of foot deformity, ankle range of motion, foot posture, local tissue water percentage, and foot pressure distribution will be evaluated in patients with chronic venous disease and lipedema.
The presence of foot deformity
The presence of foot deformity including hallux valgus, hallux limitus or rigidus, pes planus, pes cavus, toe deformities will be evaluated by inspection. In the presence of hallux valgus, its stage will be evaluated by measuring the angle using a universal goniometer, and in the presence of pes planus, the severity of pes planus will be determined by performing the navicular drop test.
Time frame: baseline of study
Plantar pressure distribution
Plantar pressure distribution (PPD) will be evaluated with EsCoSCAN® (EsCo Orthopädie Service GmbH, Germany) pedobarography. The plantar pressure in both feet will be evaluated with the force platform while standing, and the average pressure distribution percentage for each foot will be recorded.
Time frame: baseline of study
Ankle range of motion
Ankle dorsi- and plantar-flexion range of motion will be measured using a universal goniometer.
Time frame: baseline of study
Foot posture
The foot posture will be evaluated with the Foot Posture Index.
Time frame: baseline of study
Local tissue water percentage
Local tissue water percentages will be evaluated with the Moisturemeter-d compact (MMDc, Delfin Technologies, Kuopio, Finland) device.
Time frame: baseline of study
Plan to share: No
Ran from Oct 2023 to primary completion in Jan 2024, 3 months.
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This study is completed, as verified in Jan 2024. You cannot join it, but the record below documents what was studied.
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