An interventional study of Supplement 1 and Supplement 2 in Oligospermia and Sperm Count, Low, sponsored by University of Novi Sad, Faculty of Sport and Physical Education. Completed at 1 site in Serbia. Open to male participants aged 18 Years to 35 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2024-12-04.
Sponsored by University of Novi Sad, Faculty of Sport and Physical Education · Not applicable, Interventional, and Treatment
This randomized controlled double-blind parallel-group interventional trial explores the impact of 8-week creatine supplementation, with or without ubiquinol, on sperm quality biomarkers in normospermic and oligospermic men. It aims to determine potential enhancements in sperm health to provide insights into male fertility and reproductive health improvement strategies.
64 studies on the registry are indexed under Oligospermia; 17 are open to participants now.
This study's enrollment of 18 is below the median of 65 across 46 interventional studies indexed under Oligospermia.
Browse Oligospermia studies →University of Novi Sad, Faculty of Sport and Physical Education is the lead sponsor of 22 studies on the registry; none are open to participants now.
Counted across the registry records on this site, refreshed daily.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Weight in kilograms divided by height in metres squared. Example: 70 kg and 1.75 m gives 70 ÷ (1.75 × 1.75) ≈ 22.9.
What counts as overweight or obesity differs between countries (some use lower cut-offs), so go by the range the study states.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
BMI (body mass index)
Weight in kilograms divided by height in metres squared. Example: 70 kg and 1.75 m gives 70 ÷ (1.75 × 1.75) ≈ 22.9.
What counts as overweight or obesity differs between countries (some use lower cut-offs), so go by the range the study states.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Creatine monohydrate
Dietary Supplement: Supplement 1
Creatine monohydrate plus ubiquinol
Dietary Supplement: Supplement 2
Inulin
Dietary Supplement: Placebo
Creatine monohydrate (5 g/day)
Creatine monohydrate (5 g/day) plus ubiquinol (200 mg/day)
Placebo (inulin)
Sperm concentration
Number of sperm per milliliter of semen
Time frame: Change from baseline sperm concentration at 8 weeks
Total antioxidant capacity
Level of total antioxidant capacity in semen
Time frame: Change from baseline total antioxidant capacity at 8 weeks
Creatine kinase
Level of creatine kinase in semen
Time frame: Change from baseline creatine kinase at 8 weeks
Creatine
Level of creatine in semen
Time frame: Change from baseline creatine at 8 weeks
The World Health Organisation-Five Well-Being Index (WHO-5)
The World Health Organisation-Five Well-Being Index (WHO-5) is a short self-reported measure of current mental wellbeing.The raw scores are transformed to a score from 0 to 100, with lower scores indicating worse well-being.
Time frame: Change from baseline WHO-5 at 8 weeks
Plan to share: Yes — Data obtained through this study may be provided to qualified researchers with academic interest in sperm quality. Data will be coded, with no PHI included. Approval of the request and execution of all applicable agreements are prerequisites to the sharing of data with the requesting party.
Supporting information: Study protocol, Statistical analysis plan, Informed consent form, Clinical study report
Time frame: Data requests can be submitted starting 9 months after article publication and the data will be made accessible for up to 24 months. Extensions will be considered on a case-by-case basis.
Access criteria: Only qualified researchers with academic interest in sperm quality
This study is completed, as verified in Dec 2024. You cannot join it, but the record below documents what was studied.
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University of Novi Sad, Faculty of Sport and Physical Education