An interventional study of Dietary Supplement: low-dose Rosemary and Daylily extract and Dietary Supplement: medium-dose Rosemary and Daylily extract in Sleep, sponsored by University of Novi Sad, Faculty of Sport and Physical Education. Completed at 1 site in Serbia. Open to participants aged 50 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-01-02.
Sponsored by University of Novi Sad, Faculty of Sport and Physical Education · Not applicable, Interventional, and Treatment
This study aims to investigate the impact of supplementation with two different doses of Rosemary and Daylily herbal extract on various health outcomes in middle-aged adults. Over an eight-week period, the trial will assess improvements in sleep quality, circadian rhythms, energy metabolism, and relevant biochemical markers. The study employs a randomized, placebo-controlled, crossover design to evaluate the efficacy of these supplements in enhancing overall health and well-being.
University of Novi Sad, Faculty of Sport and Physical Education is the lead sponsor of 19 studies on the registry; none are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
One capsule of active Rosemary and Daylily extract and one placebo capsule
Dietary Supplement: Dietary Supplement: low-dose Rosemary and Daylily extract
Two capsules of active Rosemary and Daylily extract
Dietary Supplement: Dietary Supplement: medium-dose Rosemary and Daylily extract
Two capsules of placebo
Dietary Supplement: Dietary Supplement: control
Supplement containing Rosemary and Daylily extract
Supplement containing Rosemary and Daylily extract
Supplement containing placebo
Total sleep time
Total sleep time measured with actigraph monitor
Time frame: Change from baseline total sleep time at 8 weeks
Melatonin
Level of serum melatonin in serum
Time frame: Change from baseline serum melatonin at 8 weeks
Pittsburgh Sleep Quality Index (PSQI)
The Pittsburgh Sleep Quality Index (PSQI) is a self-report tool used to assess sleep quality and disturbances. It consists of 19 items covering seven components: sleep quality, sleep latency, sleep duration, sleep efficiency, sleep disturbances, daytime dysfunction, and use of sleep medications. Each component is scored from 0 to 3, with higher scores indicating worse sleep quality. The total score ranges from 0 to 21, where a score of 5 or higher suggests poor sleep quality. The PSQI is widely used in clinical and research settings to evaluate sleep health.
Time frame: Change from baseline PSQI at 8 weeks
Plan to share: Yes — Data obtained through this study may be provided to qualified researchers with academic interest in sleep medicine. Data will be coded, with no PHI included. Approval of the request and execution of all applicable agreements are prerequisites to the sharing of data with the requesting party.
Supporting information: Study protocol, Sap, Csr
No publications or documents are linked to this record.
This study is completed, as verified in Dec 2025. You cannot join it, but the record below documents what was studied.
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University of Novi Sad, Faculty of Sport and Physical Education