ClinicalTrials.gg
Not yet recruitingNCT06182956IRAPIDPhysioUpdated Dec 27, 2023

NIV Versus HFO for Acute Exacerbations of Interstitial Lung Diseases

An interventional study of Noninvasive mechanical ventilation and Nasal high-flow oxygen therapy in Interstitial Lung Disease and Acute Respiratory Failure, sponsored by ADIR Association. Not yet recruiting at 1 site in France. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2023-12-27.

Sponsored by ADIR Association · Not applicable, Interventional, and Treatment

Phase
Not applicable
Study type
Interventional
Enrollment
18
Allocation
Randomized
Ages
18 Years and older
Sex
All
01

Study summary

The objectives of this study are to compare the physiological consequences of high-flow oxygen therapy and noninvasive mechanical ventilation on ventilation, respiratory work and hemodynamics during acute respiratory failure in diffuse interstitial pneumonia.

02

Conditions studied

  • Interstitial Lung Disease
  • Acute Respiratory Failure

Keywords

  • Noninvasive mechanical ventilation
  • Nasal high-flow oxygen therapy
  • Respiratory work
  • Hemodynamics
  • Diaphragm
03

In context

Lung Diseases, Interstitial

680 studies on the registry are indexed under Lung Diseases, Interstitial; 246 are open to participants now.

This study's planned enrollment of 18 is below the median of 60 across 384 interventional studies indexed under Lung Diseases, Interstitial.

Browse Lung Diseases, Interstitial studies →

Lead sponsor

ADIR Association is the lead sponsor of 27 studies on the registry; 7 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Age > 18 yrs
  • Hospitalization in intensive care unit
  • Acute exacerbation of a previously/presently documented diffuse (fibrotic) interstitial lung disease
  • Dyspnea majoration since at least 1 month
  • Alveolar or ground-glass opacities on CT-scan that are superposed to interstitial lung disease and not explained by left heart failure or volume overload
  • Hypoxemia requiring oxygen flows > 6 L/min

Exclusion criteria

Exclusion criteria:

  • to noninvasive ventilation or high-flow oxygen therapy
  • Immediate indication to endotracheal intubation or hemodynamic assistance
  • > 40
  • Presence of a pacemaker or an implantable defibrillator
  • Presence of cutaneous lesions where Pulmovista® belt should be placed
  • Moribund patient
  • Pregnant or breastfeeding women or women of childbearing age without an effective method of
  • Protected adult patient (tutorship or curatorship)
  • Patient deprived of liberty by court or administrative decision
  • No possibility to install nasogastric tube
  • Endotracheal or tracheostomy tube requirement during the study
  • Hemodynamic assistance requirement during the study
Terms in these criteria, in plain language(3)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

Contraindication

A reason a treatment, test or procedure should not be given to a particular person, such as an allergy, another illness or a medicine they take.

BMI (body mass index)

Weight in kilograms divided by height in metres squared. Example: 70 kg and 1.75 m gives 70 ÷ (1.75 × 1.75) ≈ 22.9.

What counts as overweight or obesity differs between countries (some use lower cut-offs), so go by the range the study states.

Contraception

Ways of preventing pregnancy. “Highly effective” methods fail less than 1% of the time a year when used correctly — for example an IUD or an implant.

Criteria usually say which methods count and how long to keep using them after the last dose, sometimes for male participants too. Some studies accept a partner’s vasectomy if it was confirmed successful and that person is the participant’s only sexual partner.

05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Crossover assignment
Masking
None (open label)
Enrollment
18 participants (estimated)

Study arms

  • Experimental
    NIV + CPAP + HFO

    The patient will be placed under noninvasive mechanical ventilation during 30 min, then continuous positive airway pressure during 30 min and then nasal high-flow oxygen during 30 min. Each period will be separated by a washout period of maximum 30 min under oxygen with a non-rebreathing mask.

    Device: Noninvasive mechanical ventilation · Device: Nasal high-flow oxygen therapy · Device: Continuous positive airway pressure

  • Experimental
    NIV + HFO + CPAP

    The patient will be placed under noninvasive mechanical ventilation during 30 min, then nasal high-flow oxygen during 30 min and then continuous positive airway pressure during 30 min. Each period will be separated by a washout period of maximum 30 min under oxygen with a non-rebreathing mask.

    Device: Noninvasive mechanical ventilation · Device: Nasal high-flow oxygen therapy · Device: Continuous positive airway pressure

  • Experimental
    CPAP + NIV + HFO

    The patient will be placed under continuous positive airway pressure during 30 min, then noninvasive mechanical ventilation during 30 min and then nasal high-flow oxygen during 30 min. Each period will be separated by a washout period of maximum 30 min under oxygen with a non-rebreathing mask.

    Device: Noninvasive mechanical ventilation · Device: Nasal high-flow oxygen therapy · Device: Continuous positive airway pressure

  • Experimental
    CPAP + HFO + NIV

    The patient will be placed under continuous positive airway pressure during 30 min, then nasal high-flow oxygen during 30 min and then noninvasive mechanical ventilation during 30 min. Each period will be separated by a washout period of maximum 30 min under oxygen with a non-rebreathing mask.

    Device: Noninvasive mechanical ventilation · Device: Nasal high-flow oxygen therapy · Device: Continuous positive airway pressure

  • Experimental
    HFO + CPAP + NIV

    The patient will be placed under nasal high-flow oxygen during 30 min, then continuous positive airway pressure during 30 min and then noninvasive mechanical ventilation during 30 min. Each period will be separated by a washout period of maximum 30 min under oxygen with a non-rebreathing mask.

    Device: Noninvasive mechanical ventilation · Device: Nasal high-flow oxygen therapy · Device: Continuous positive airway pressure

  • Experimental
    HFO + NIV + CPAP

    The patient will be placed under nasal high-flow oxygen during 30 min, then noninvasive mechanical ventilation during 30 min and then continuous positive airway pressure during 30 min. Each period will be separated by a washout period of maximum 30 min under oxygen with a non-rebreathing mask.

    Device: Noninvasive mechanical ventilation · Device: Nasal high-flow oxygen therapy · Device: Continuous positive airway pressure

Interventions

  • DeviceNoninvasive mechanical ventilation

    Noninvasive mechanical ventilation is a respiratory technique which allows the administration of positive inspiratory and expiratory airway pressures in order to ventilate the lungs.

  • DeviceNasal high-flow oxygen therapy

    Nasal high-flow is a respiratory technique which allows the administration of warmed and humidified air, associated with oxygen.

  • DeviceContinuous positive airway pressure

    Continuous positive airway pressure is a respiratory technique which allows to maintain a constant positive airway pressure during inspiration and expiration.

06

What researchers measure

Primary outcomes

  1. Pulmonary compliance

    Comparison of global pulmonary compliance (Cglob) under noninvasive ventilation (NIV) and high-flow oxygen therapy (HFO) during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

Secondary outcomes

  1. Pulmonary compliance

    Comparison of global pulmonary compliance (Cglob) under NIV and continuous positive airway pressure (CPAP) during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  2. Pulmonary compliance

    Comparison of global pulmonary compliance (Cglob) under HFO and CPAP during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  3. Pulmonary compliance

    Comparison of global pulmonary compliance (Cglob) under HFO and face mask oxygen therapy (FM) during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  4. Pulmonary compliance

    Comparison of global pulmonary compliance (Cglob) under NIV and face mask oxygen therapy (FM) during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  5. Pulmonary compliance

    Comparison of global pulmonary compliance (Cglob) under CPAP and face mask oxygen therapy (FM) during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  6. Tidal volume

    Comparison of Tidal volume under CPAP and face mask oxygen therapy (FM) during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  7. Tidal volume

    Comparison of Tidal volume under HFO and FM during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  8. Tidal volume

    Comparison of Tidal volume under NIV and FM during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  9. Tidal volume

    Comparison of Tidal volume under HFO and NIV during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  10. Tidal volume

    Comparison of Tidal volume under HFO and CPAP during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  11. Tidal volume

    Comparison of Tidal volume under NIV and CPAP during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  12. end-expiratory lung volume

    Comparison of end-expiratory lung volume under NIV and CPAP during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  13. end-expiratory lung volume

    Comparison of end-expiratory lung volume under NIV and HFO during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  14. end-expiratory lung volume

    Comparison of end-expiratory lung volume under NIV and FM during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  15. end-expiratory lung volume

    Comparison of end-expiratory lung volume under HFO and FM during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  16. end-expiratory lung volume

    Comparison of end-expiratory lung volume under HFO and CPAP during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  17. end-expiratory lung volume

    Comparison of end-expiratory lung volume under FM and CPAP during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  18. transpulmonary pressure

    Comparison of transpulmonary pressure under FM and CPAP during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  19. transpulmonary pressure

    Comparison of transpulmonary pressure under FM and HFO during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  20. transpulmonary pressure

    Comparison of transpulmonary pressure under FM and NIV during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  21. transpulmonary pressure

    Comparison of transpulmonary pressure under HFO and NIV during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  22. transpulmonary pressure

    Comparison of transpulmonary pressure under HFO and CPAP during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  23. transpulmonary pressure

    Comparison of transpulmonary pressure under NIV and CPAP during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  24. driving pressure

    Comparison of driving pressure under NIV and CPAP during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  25. driving pressure

    Comparison of driving pressure under NIV and HFO during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  26. driving pressure

    Comparison of driving pressure under NIV and FM during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  27. driving pressure

    Comparison of driving pressure under HFO and FM during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  28. driving pressure

    Comparison of driving pressure under CPAP and HFO during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  29. driving pressure

    Comparison of driving pressure under CPAP and FM during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  30. Global inhomogeneity index

    Comparison of Global inhomogeneity index under CPAP and FM during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  31. Global inhomogeneity index

    Comparison of Global inhomogeneity index under HFO and FM during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  32. Global inhomogeneity index

    Comparison of Global inhomogeneity index under NIV and FM during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  33. Global inhomogeneity index

    Comparison of Global inhomogeneity index under NIV and HFO during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  34. Global inhomogeneity index

    Comparison of Global inhomogeneity index under NIV and CPAP during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  35. Global inhomogeneity index

    Comparison of Global inhomogeneity index under HFO and CPAP during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  36. respiratory rate

    Comparison of respiratory rate under HFO and CPAP during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  37. respiratory rate

    Comparison of respiratory rate under HFO and NIV during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  38. respiratory rate

    Comparison of respiratory rate under HFO and FM during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  39. respiratory rate

    Comparison of respiratory rate under CPAP and FM during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  40. respiratory rate

    Comparison of respiratory rate under NIV and FM during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  41. respiratory rate

    Comparison of respiratory rate under NIV and CPAP during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  42. inspiratory time

    Comparison of inspiratory time under NIV and CPAP during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  43. inspiratory time

    Comparison of inspiratory time under NIV and HFO during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  44. inspiratory time

    Comparison of inspiratory time under NIV and FM during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  45. inspiratory time

    Comparison of inspiratory time under HFO and FM during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  46. inspiratory time

    Comparison of inspiratory time under CPAP and FM during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  47. inspiratory time

    Comparison of inspiratory time under CPAP and NIV during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  48. inspiratory time

    Comparison of inspiratory time under CPAP and HFO during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  49. oesophagal pressure swings

    Comparison of oesophagal pressure variations between inspiration and expiration under CPAP and HFO during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  50. oesophagal pressure swings

    Comparison of oesophagal pressure variations between inspiration and expiration under CPAP and NIV during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  51. oesophagal pressure swings

    Comparison of oesophagal pressure variations between inspiration and expiration under CPAP and FM during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  52. oesophagal pressure swings

    Comparison of oesophagal pressure variations between inspiration and expiration under HFO and FM during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  53. oesophagal pressure swings

    Comparison of oesophagal pressure variations between inspiration and expiration under NIV and FM during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  54. oesophagal pressure swings

    Comparison of oesophagal pressure variations between inspiration and expiration under NIV and HFO during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  55. transdiaphragmatic pressure variations

    Comparison of transdiaphragmatic pressure variations between inspiration and expiration under NIV and HFO during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  56. transdiaphragmatic pressure variations

    Comparison of transdiaphragmatic pressure variations between inspiration and expiration under NIV and CPAP during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  57. transdiaphragmatic pressure variations

    Comparison of transdiaphragmatic pressure variations between inspiration and expiration under NIV and FM during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  58. transdiaphragmatic pressure variations

    Comparison of transdiaphragmatic pressure variations between inspiration and expiration under CPAP and FM during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  59. transdiaphragmatic pressure variations

    Comparison of transdiaphragmatic pressure variations between inspiration and expiration under HFO and FM during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  60. transdiaphragmatic pressure variations

    Comparison of transdiaphragmatic pressure variations between inspiration and expiration under HFO and CPAP during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  61. transdiaphragmatic pressure time products

    Comparison of transdiaphragmatic pressure time products under HFO and CPAP during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  62. transdiaphragmatic pressure time products

    Comparison of transdiaphragmatic pressure time products under HFO and NIV during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  63. transdiaphragmatic pressure time products

    Comparison of transdiaphragmatic pressure time products under HFO and FM during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  64. transdiaphragmatic pressure time products

    Comparison of transdiaphragmatic pressure time products under CPAP and FM during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  65. transdiaphragmatic pressure time products

    Comparison of transdiaphragmatic pressure time products under NIV and FM during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  66. transdiaphragmatic pressure time products

    Comparison of transdiaphragmatic pressure time products under NIV and CPAP during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  67. oesophagal pressure time products

    Comparison of oesophagal pressure time products under NIV and CPAP during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  68. oesophagal pressure time products

    Comparison of oesophagal pressure time products under NIV and HFO during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  69. oesophagal pressure time products

    Comparison of oesophagal pressure time products under NIV and FM during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  70. oesophagal pressure time products

    Comparison of oesophagal pressure time products under CPAP and FM during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  71. oesophagal pressure time products

    Comparison of oesophagal pressure time products under HFO and FM during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  72. oesophagal pressure time products

    Comparison of oesophagal pressure time products under HFO and CPAP during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  73. ultrasound diaphragmatic strain.

    Comparison of ultrasound diaphragmatic strain under HFO and CPAP during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  74. diaphragmatic thickening fraction

    Comparison of diaphragmatic thickening fraction under HFO and CPAP during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  75. diaphragmatic thickening fraction

    Comparison of diaphragmatic thickening fraction under HFO and NIV during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  76. diaphragmatic thickening fraction

    Comparison of diaphragmatic thickening fraction under HFO and FM during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  77. diaphragmatic thickening fraction

    Comparison of diaphragmatic thickening fraction under CPAP and FM during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  78. diaphragmatic thickening fraction

    Comparison of diaphragmatic thickening fraction under NIV and FM during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  79. diaphragmatic thickening fraction

    Comparison of diaphragmatic thickening fraction under NIV and CPAP during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  80. peak inspiratory flow

    Comparison of peak inspiratory flow under NIV and CPAP during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  81. peak inspiratory flow

    Comparison of peak inspiratory flow under NIV and HFO during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  82. peak inspiratory flow

    Comparison of peak inspiratory flow under NIV and FM during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  83. peak inspiratory flow

    Comparison of peak inspiratory flow under HFO and FM during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  84. peak inspiratory flow

    Comparison of peak inspiratory flow under HFO and CPAP during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  85. peak inspiratory flow

    Comparison of peak inspiratory flow under FM and CPAP during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  86. peak expiratory flow

    Comparison of peak expiratory flow under FM and CPAP during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  87. peak expiratory flow

    Comparison of peak expiratory flow under FM and NIV during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  88. peak expiratory flow

    Comparison of peak expiratory flow under FM and HFO during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  89. peak expiratory flow

    Comparison of peak expiratory flow under CPAP and HFO during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  90. peak expiratory flow

    Comparison of peak expiratory flow under CPAP and NIV during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  91. peak expiratory flow

    Comparison of peak expiratory flow under HFO and NIV during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  92. Systolic arterial pressures

    Comparison of Systolic arterial pressures under NIV and CPAP during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  93. Systolic arterial pressures

    Comparison of Systolic arterial pressures under NIV and HFO during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  94. Systolic arterial pressures

    Comparison of Systolic arterial pressures under NIV and FM during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  95. Systolic arterial pressures

    Comparison of Systolic arterial pressures under HFO and FM during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  96. Systolic arterial pressures

    Comparison of Systolic arterial pressures under CPAP and FM during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  97. Systolic arterial pressures

    Comparison of Systolic arterial pressures under CPAP and HFO during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  98. Diastolic arterial pressures

    Comparison of Diastolic arterial pressures under CPAP and HFO during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  99. Diastolic arterial pressures

    Comparison of Diastolic arterial pressures under CPAP and NIV during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  100. Diastolic arterial pressures

    Comparison of Diastolic arterial pressures under CPAP and FM during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  101. Diastolic arterial pressures

    Comparison of Diastolic arterial pressures under NIV and FM during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  102. Diastolic arterial pressures

    Comparison of Diastolic arterial pressures under HFO and FM during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  103. Diastolic arterial pressures

    Comparison of Diastolic arterial pressures under HFO and NIV during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  104. Mean arterial pressure

    Comparison of Mean arterial pressures under HFO and NIV during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  105. Mean arterial pressure

    Comparison of Mean arterial pressures under HFO and CPAP during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  106. Mean arterial pressure

    Comparison of Mean arterial pressures under HFO and FM during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  107. Mean arterial pressure

    Comparison of Mean arterial pressures under CPAP and FM during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  108. Mean arterial pressure

    Comparison of Mean arterial pressures under NIV and FM during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  109. Mean arterial pressure

    Comparison of Mean arterial pressures under NIV and CPAP during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  110. systolic pulmonary arterial pressure

    Comparison of systolic pulmonary arterial pressure under NIV and CPAP during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  111. systolic pulmonary arterial pressure

    Comparison of systolic pulmonary arterial pressure under NIV and HFO during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  112. systolic pulmonary arterial pressure

    Comparison of systolic pulmonary arterial pressure under NIV and FM during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  113. systolic pulmonary arterial pressure

    Comparison of systolic pulmonary arterial pressure under HFO and FM during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  114. systolic pulmonary arterial pressure

    Comparison of systolic pulmonary arterial pressure under CPAP and FM during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  115. systolic pulmonary arterial pressure

    Comparison of systolic pulmonary arterial pressure under CPAP and NIV during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  116. tricuspid annular plane systolic excursion

    Comparison of tricuspid annular plane systolic excursion under CPAP and NIV during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  117. tricuspid annular plane systolic excursion

    Comparison of tricuspid annular plane systolic excursion under CPAP and HFO during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  118. tricuspid annular plane systolic excursion

    Comparison of tricuspid annular plane systolic excursion under CPAP and FM during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  119. tricuspid annular plane systolic excursion

    Comparison of tricuspid annular plane systolic excursion under NIV and FM during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  120. tricuspid annular plane systolic excursion

    Comparison of tricuspid annular plane systolic excursion under HFO and FM during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  121. tricuspid annular plane systolic excursion

    Comparison of tricuspid annular plane systolic excursion under HFO and NIV during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  122. right ventricular strain

    Comparison of right ventricular strain under HFO and NIV during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  123. right ventricular strain

    Comparison of right ventricular strain under HFO and CPAP during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  124. right ventricular strain

    Comparison of right ventricular strain under HFO and FM during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  125. right ventricular strain

    Comparison of right ventricular strain under NIV and FM during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  126. right ventricular strain

    Comparison of right ventricular strain under CPAP and FM during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  127. right ventricular strain

    Comparison of right ventricular strain under CPAP and NIV during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  128. left ventricular ejection fraction

    Comparison of left ventricular ejection fraction under CPAP and NIV during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  129. left ventricular ejection fraction

    Comparison of left ventricular ejection fraction under CPAP and HFO during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  130. left ventricular ejection fraction

    Comparison of left ventricular ejection fraction under CPAP and FM during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  131. left ventricular ejection fraction

    Comparison of left ventricular ejection fraction under NIV and FM during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  132. left ventricular ejection fraction

    Comparison of left ventricular ejection fraction under HFO and FM during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  133. left ventricular ejection fraction

    Comparison of left ventricular ejection fraction under HFO and NIV during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  134. E/E' ratio

    Comparison of E/E' ratio under HFO and NIV during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  135. E/E' ratio

    Comparison of E/E' ratio under HFO and CPAP during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  136. E/E' ratio

    Comparison of E/E' ratio under HFO and FM during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  137. E/E' ratio

    Comparison of E/E' ratio under NIV and FM during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  138. E/E' ratio

    Comparison of E/E' ratio under CPAP and FM during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  139. E/E' ratio

    Comparison of E/E' ratio under CPAP and NIV during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  140. right auricular pressure

    Comparison of right auricular pressure under CPAP and NIV during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  141. right auricular pressure

    Comparison of right auricular pressure under CPAP and HFO during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  142. right auricular pressure

    Comparison of right auricular pressure under CPAP and FM during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  143. right auricular pressure

    Comparison of right auricular pressure under NIV and FM during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  144. right auricular pressure

    Comparison of right auricular pressure under HFO and FM during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  145. right auricular pressure

    Comparison of right auricular pressure under HFO and NIV during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  146. cardiac output

    Comparison of cardiac output under HFO and NIV during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  147. cardiac output

    Comparison of cardiac output under HFO and CPAP during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  148. cardiac output

    Comparison of cardiac output under HFO and FM during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  149. cardiac output

    Comparison of cardiac output under NIV and FM during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  150. cardiac output

    Comparison of cardiac output under CPAP and FM during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  151. cardiac output

    Comparison of cardiac output under CPAP and NIV during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  152. heart rate

    Comparison of heart rate under CPAP and NIV during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  153. heart rate

    Comparison of heart rate under CPAP and HFO during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  154. heart rate

    Comparison of heart rate under CPAP and FM during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  155. heart rate

    Comparison of heart rate under HFO and FM during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  156. heart rate

    Comparison of heart rate under NIV and FM during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  157. heart rate

    Comparison of heart rate under NIV and HFO during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  158. Pulsed oxymetry

    Comparison of pulsed oxymetry under NIV and HFO during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  159. Pulsed oxymetry

    Comparison of pulsed oxymetry under NIV and CPAP during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  160. Pulsed oxymetry

    Comparison of pulsed oxymetry under NIV and FM during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  161. Pulsed oxymetry

    Comparison of pulsed oxymetry under HFO and FM during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  162. Pulsed oxymetry

    Comparison of pulsed oxymetry under CPAP and FM during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  163. Pulsed oxymetry

    Comparison of pulsed oxymetry under CPAP and HFO during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  164. transcutaneous carbon dioxide pressure

    Comparison of transcutaneous carbon dioxide pressure under CPAP and HFO during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  165. transcutaneous carbon dioxide pressure

    Comparison of transcutaneous carbon dioxide pressure under CPAP and FM during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  166. transcutaneous carbon dioxide pressure

    Comparison of transcutaneous carbon dioxide pressure under CPAP and NIV during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  167. transcutaneous carbon dioxide pressure

    Comparison of transcutaneous carbon dioxide pressure under FM and NIV during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  168. transcutaneous carbon dioxide pressure

    Comparison of transcutaneous carbon dioxide pressure under HFO and NIV during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  169. transcutaneous carbon dioxide pressure

    Comparison of transcutaneous carbon dioxide pressure under HFO and FM during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  170. Dyspnea

    Comparison of Borg's scale (from 0 to 10, 10 is maximal dyspnea) under HFO and FM during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  171. Dyspnea

    Comparison of Borg's scale (from 0 to 10, 10 is maximal dyspnea) under HFO and NIV during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  172. Dyspnea

    Comparison of Borg's scale (from 0 to 10, 10 is maximal dyspnea) under HFO and CPAP during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  173. Dyspnea

    Comparison of Borg's scale (from 0 to 10, 10 is maximal dyspnea) under NIV and CPAP during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  174. Dyspnea

    Comparison of Borg's scale (from 0 to 10, 10 is maximal dyspnea) under FM and CPAP during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  175. Dyspnea

    Comparison of Borg's scale (from 0 to 10, 10 is maximal dyspnea) under FM and NIV during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  176. Comparison of Comfort

    Visual comfort scale (from 0 to 10, 10 is maximal confort) under FM and NIV during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  177. Comparison of Comfort

    Visual comfort scale (from 0 to 10, 10 is maximal confort) under FM and HFO during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  178. Comparison of Comfort

    Visual comfort scale (from 0 to 10, 10 is maximal confort) under FM and CPAP during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  179. Comparison of Comfort

    Visual comfort scale (from 0 to 10, 10 is maximal confort) under NIV and CPAP during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  180. Comparison of Comfort

    Visual comfort scale (from 0 to 10, 10 is maximal confort) under HFO and CPAP during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

  181. Comparison of Comfort

    Visual comfort scale (from 0 to 10, 10 is maximal confort) under HFO and NIV during acute respiratory failure in diffuse interstitial pneumonia.

    Time frame: During the intervention, after an exposure of 30 minutes to the oxygen therapy device

07

Study locations

1 site
  • ADIR Association
    Rouen, 76000, France
    • Elise ARTAUD-MACARI, MD · Contactelise.artaud-macari@chu-rouen.fr · +33232885992
    • David DEBEAUMONT, MD · Sub investigator
    • Christophe GIRAULT, MD · Sub investigator
    • Antoine CUVELIER, MD, PHD · Sub investigator
    • Pierre Alexandre ROGER, MD · Sub investigator
    • Gurvan LEBOUAR, MD · Sub investigator
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Dec 27, 2023, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT06182956
Lead sponsor
ADIR Association
Responsible party
Sponsor
First posted
Dec 27, 2023
Start date
Jan 1, 2024 (estimated)
Primary completion
Dec 31, 2026 (estimated)
Completion
Dec 31, 2026 (estimated)
Last update
Dec 27, 2023

Study contacts

Elise ARTAUD-MACARI, MD
Contact
elise.artaud-macari@chu-rouen.fr
+33232885992
Maryline LEFORT
Contact
mlefort@adir-hautenormandie.com
+33232885992
Elise ARTAUD-MACARI, MD
principal investigator · University Hospital, Rouen

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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