An interventional study of glass hybrid restorative system and Fluoride varnish + Glass hybrid restorative system in Molar-Incisor Hypomineralisation, sponsored by Marmara University. Completed at 1 site in Turkey (Türkiye). Open to participants aged 8 Years to 13 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-04-06.
Sponsored by Marmara University · Not applicable, Interventional, and Treatment
The objective of this study is to assess the efficacy of silver diamine fluoride application in molars affected by molar-incisor hypomineralization. Additionally, the study aims to evaluate the effectiveness of the combined application of silver diamine fluoride, commonly used for dentin hypersensitivity, with a glass hybrid restorative system. The goal is to mitigate sensitivity and improve chewing functions in teeth affected by molar-incisor hypomineralization.
In a research study focusing on 120 children aged 8-13 with molar incisor hypomineralization (MIH), a comprehensive examination of 240 teeth will be conducted. Study will employ selective caries removal to eliminate decay and subsequently apply restorations. The two intervention groups are delineated as follows:
Group 1: Glass hybrid restorative system (Equia Forte, GC Europe, Leuven, Belgium)
Group 2 : Restoration involving fluoride varnish (SDI Riva Star) + glass hybrid restorative system (Equia Forte, GC Europe, Leuven, Belgium)
121 studies on the registry are indexed under Molar Hypomineralization; 41 are open to participants now.
This study's enrollment of 34 is below the median of 52 across 94 interventional studies indexed under Molar Hypomineralization.
Browse Molar Hypomineralization studies →Marmara University is the lead sponsor of 576 studies on the registry; 136 are open to participants now.
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Exclusion Criteria:
(Equia Forte, GC Europe, Leuven, Belgium)
Other: glass hybrid restorative system
Fluoride varnish (SDI Riva Star)+ Glass hybrid restorative (Equia Forte, GC Europe, Leuven, Belgium)
Other: Fluoride varnish + Glass hybrid restorative system
In the teeth where the indication is identified, selective caries removal will be performed to eliminate the decayed tooth tissue. Subsequently, for each patient in the study apply glass hybrid restorative system (Equia Forte, GC Europe, Leuven, Belgium)
In the teeth where the indication is identified, selective caries removal will be performed to eliminate the decayed tooth tissue. Subsequently, for each patient in the study apply Fluoride varnish (SDI Riva Star)+ Glass hybrid restorative (Equia Forte, GC Europe, Leuven, Belgium)
United States Public Health Service (USPHS): Retention, marginal compliance and gingival health criteria
Restorations were evaluated to determine success according to modified United States Public Health Service (USPHS) criteria for marginal adaptation, marginal discolouration, secondary caries, anatomical form, retention, postoperative sensitivity and colour matching. Restorations with an "Alpha (A)" score were considered successful, those with a "Bravo (B)" score were considered acceptable, and those with a "Charlie (C)" score were considered unsuccessful. The scoring of the restorations was decided by agreement of both dentists (Ryge G. et al., 1980).
Time frame: 1.5 -2 year
The Schiff Cold Air Sensitivity Score
The Schiff Cold Air Sensitivity Score is a test conducted in dental units. Cold air from a spray is applied to the surface of the tooth's dentin, 2-3 mm away, and at a 90-degree angle, with continuous pressure of 45-60 PSI for 2-3 seconds, following the isolation of neighboring teeth. The temperature should be around 20 degrees Celsius. The patient's pain level is then scored by the dentist using a scale. * Score 0: No response to the stimulus. * Score 1: Responds to the stimulus but does not request it to be stopped. * Score 2: Responds to the stimulus, requests it to be stopped, or makes movements to avoid it. * Score 3: Responds to the stimulus, finds it painful, and requests it to be stopped.
Time frame: 1.5-2 year
This study is completed, as verified in Mar 2026. You cannot join it, but the record below documents what was studied.
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Marmara University