An observational study in Malnutrition, sponsored by University of Tartu. Recruiting at 1 site in Estonia. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2025-03-28.
Sponsored by University of Tartu · Observational
This observational study of aims to test whether and how the results of GLIM change when using different approaches and methods to carry out its components.
The main questions the study aims to answer are:
Participants will be/have:
1,277 studies on the registry are indexed under Malnutrition; 230 are open to participants now.
This study's planned enrollment of 300 is above the median of 206 across 393 observational studies indexed under Malnutrition.
Browse Malnutrition studies →University of Tartu is the lead sponsor of 46 studies on the registry; 13 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Inpatients of day patients admitted to the Tartu University Hospital.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Inclusion Criteria: Age of 18+ years, able and willing to sign the consent form, inpatients of the Tartu University Hospital, admitted within 72 hours before enrolment. Exclusion Criteria: Age of \<18 years, inability or refusal to sign the consent form, pregnant or lactating women, more than 72 hours passed since admission, patients isolating with an infection.
Diagnostic Test: Nutrition screening and assessment
The patient is interviewed for changes in body weight in the last six months and food intake in the last two weeks. The investigator evaluates the patient's diet, symptoms related to their nutritional status, and functional capacity according to the Subjective Global Assessment (SGA). The SGA tool itself is completed by the researcher. Height and weight of the patient are measured, if not yet recorded, and BMI is calculated. The patient's muscle mass is measured using mid-upper arm circumference (MUAC), calf circumference (CC) and bioelectrical impedance (BIA), and their muscle function assessed using hand grip strength.
Subjective Global Assessment (SGA) defined malnutrition
Subjective Global Assessment (SGA) can be considered a method that is close to a "gold standard" for malnutrition assessment. Therefore, the study will analyse how different approaches to screening and muscle mass measurement affect the performance of GLIM in detecting Subjective Global Assessment (SGA) defined malnutrition.
Time frame: baseline, pre-intervention/procedure/surgery
One-year mortality
One year after the data collection, we will look at the patient records to collect the 1-year mortality data. This will give information about whether and how different approaches to components of GLIM affect its ability to predict one-year mortality.
Time frame: through study completion, an average of 1 year
Computed tomography (CT) defined muscle mass
One of the GLIM criteria is "reduced muscle mass", and this study will investigate how muscle mass measured with simpler methods compares against muscle mass measured with CT.
Time frame: baseline, pre-intervention/procedure/surgery
DEXA defined muscle mass
One of the GLIM criteria is "reduced muscle mass", and this study will investigate how muscle mass measured with simpler methods compares against muscle mass measured with DEXA.
Time frame: baseline, pre-intervention/procedure/surgery
Bioelectrical impedance (BIA) defined muscle mass
One of the GLIM criteria is "reduced muscle mass", and this study will investigate how muscle mass measured with simpler methods compares against muscle mass measured with BIA.
Time frame: baseline, pre-intervention/procedure/surgery
Eligibility is decided by the study team. Share this record with your doctor or contact the team directly.
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University of Tartu