An interventional study of Effect on contrast media depending on the time of its administratsion in Small Bowel Obstruction, sponsored by University of Tartu. Recruiting at 1 site in Estonia. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2025-03-30.
Sponsored by University of Tartu · Not applicable, Interventional, and Diagnostic
Patients hospitalized with adhesive small bowel obstruction (SBO) are randomized to 2 study groups at admission after signing an informed consent form. Water-soluble contrast media (CM) will be administered after 4 or after 24 hours of nasogastric- tube decompression.
Patients presenting with symptoms of small bowel obstruction (SBO) will be evaluated and if the diagnosis of adhesive small bowel obstruction is made it must be decided what is the treatment of choice.
If immediate surgery is needed- it will not be delayed If patients are eligible for conservative management- they will be randomized to 2 study groups- contrast media (CM) after 4 hours of nasogastric-tube decompression and after 24 hours of nasogastric-tube decompression.
Contrast media challenge acquires radiographs (X-rays) to be taken after an interval (common practice) decided by the surgeon.
If at any point patient needs surgery- it will not be delayed. The results are compared. The hypothesis is, that if CM is administered sooner- it will help SBO resolution
University of Tartu is the lead sponsor of 46 studies on the registry; 13 are open to participants now.
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Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Patients will receive contrast media after 4 hours of nasogastric decompression
Other: Effect on contrast media depending on the time of its administratsion
Patients will receive contrast media after 24 hours of nasogastric decompression
Other: Effect on contrast media depending on the time of its administratsion
CM is a common practice when it comes to the management of small bowel obstruction. However there is no consensus as when it should be administered
SBO resolution
SBO resolution with conservative measures * passing gas * bowel movement * CM in the colon on the X-ray
Time frame: Period of hospitalization- approximately 5 days
Plan to share: Undecided
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