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CompletedNCT06157606Updated Jul 8, 2025

Prediction Model for Inadequate Weight Loss After Sleeve Gastrectomy

An observational study in Bariatric Surgery, Sleeve Gastrectomy and Weight Loss, sponsored by China-Japan Friendship Hospital. Completed at 1 site in China. Open to participants aged 16 Years to 70 Years. Per ClinicalTrials.gov, last updated 2025-07-08.

Sponsored by China-Japan Friendship Hospital · Observational

Study type
Observational
Model
Cohort
Time perspective
Other
Enrollment
1,000
Ages
16 Years to 70 Years
Sex
All
01

Study summary

This study aims to develop and validate a prediction model for estimating the probability of inadequate weight loss one year after sleeve gastrectomy.

Read the detailed description

Inadequate weight loss (IWL) is a major problem after sleeve gastrectomy, leading to the recurrence of obesity-related comorbidities and increased risk of revision surgery. It is important to identify the high-risk individuals for IWL before surgery so that clinicians can initiate more rigorous weight monitoring and management strategies. Therefore, this study aims to develop a prediction model using preoperative clinical and laboratory data to estimate the risk of IWL one year after sleeve gastrectomy, and then validate it using two separate datasets.

02

Conditions studied

  • Bariatric Surgery
  • Sleeve Gastrectomy
  • Weight Loss

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Keywords

  • Sleeve Gastrectomy
  • Weight Loss
  • Prediction Model
03

In context

Weight Loss

1,766 studies on the registry are indexed under Weight Loss; 277 are open to participants now.

This study's enrollment of 1,000 is above the median of 92 across 219 observational studies indexed under Weight Loss.

Browse Weight Loss studies →

Lead sponsor

China-Japan Friendship Hospital is the lead sponsor of 173 studies on the registry; 109 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
16 Years to 70 Years
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Probability sample

Study population

The population included patients with obesity who received sleeve gastrectomy between September 2017 and September 2024. All patients were followed up for at least 1 year.

Inclusion criteria

  • BMI ≥ 27.5 kg/m2;
  • 16 years ≤ age ≤ 70 years;
  • Complete preoperative data and one-year follow-up information

Exclusion criteria

Exclusion Criteria:

  • Patients who did not undergo SG;
  • Incomplete follow-up information;
  • Patients with a history of pituitary or thyroid disease;
  • Female patients who conceived within one year after surgery
05

Study design

Observational model
Cohort
Time perspective
Other
Enrollment
1,000 participants (actual)
Target follow-up
1 Year
Patient registry
Yes
06

What researchers measure

Primary outcomes

  1. Area under receiver operating characteristic curve (AUC) of the prediction model

    AUC reflects the discriminatory ability of the model, which was measured in this study.

    Time frame: 1 year

Secondary outcomes

  1. Brier score of the prediction model

    Brier score reflects the calibration of the model, which was measured in this study.

    Time frame: 1 year

07

Study locations

1 site
  • Yuntao Nie
    Beijing, 100029, China
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jul 8, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT06157606
Lead sponsor
China-Japan Friendship Hospital
Collaborators
The Second Hospital of Shandong University, Jining First People's Hospital
Responsible party
Yuntao Nie (Medical doctor, China-Japan Friendship Hospital) — Principal investigator
First posted
Dec 6, 2023
Start date
Sep 1, 2017
Primary completion
Sep 30, 2024
Completion
Sep 30, 2024
Last update
Jul 8, 2025

Study contacts

Yuntao Nie, M.D.
principal investigator · China-Japan Friendship Hospital
Yinlu Ding, M.D.
study director · The Second Hospital of Shandong University
Ming Zhu, M.D.
study director · Jining First People's Hospital

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Jul 2025. You cannot join it, but the record below documents what was studied.

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