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CompletedNCT06120452Updated Aug 23, 2024

A Clinical Trial to Evaluate the Effectiveness of an Acne Serum in Improving Facial Acne and Post-Acne Pigmentation

An interventional study of Rael Miracle Clear Complete Acne Serum in Acne, sponsored by Rael. Completed at 1 site in United States. Open to female participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2024-08-23.

Sponsored by Rael · Not applicable, Interventional, and Other

Phase
Not applicable
Study type
Interventional
Enrollment
40
Allocation
Not applicable
Ages
18 Years and older
Sex
Female
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Study summary

This study will evaluate the efficacy of the Rael Miracle Clear Complete Acne Serum product in improving facial acne and post-acne pigmentation. This study will last for 56 days. The study will be conducted as a single-arm trial where all participants will use the test products. Participants will be required to complete questionnaires at Baseline, Day 1, Day 3, Day 7, Day 14, Day 28, and Day 56. Photos will be taken at Baseline, Day 28, and Day 56. The photos from Baseline and Day 56 will undergo expert skin grading

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Conditions studied

  • Acne

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03

In context

Acne Vulgaris

730 studies on the registry are indexed under Acne Vulgaris; 86 are open to participants now.

This study's enrollment of 40 is below the median of 69 across 628 interventional studies indexed under Acne Vulgaris.

Browse Acne Vulgaris studies →

Lead sponsor

Rael is the lead sponsor of 5 studies on the registry; none are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years and older
Sexes eligible
Female
Accepts healthy volunteers
Yes

Inclusion criteria

  • Female. Age 18+. Currently experiencing mild to moderate acne issues. Generally healthy -and not living with any uncontrolled chronic disease.

Exclusion criteria

Exclusion Criteria:

  • Anyone with pre-existing chronic conditions that would prevent participants from adhering to the protocol, including oncological and psychiatric disorders.

Anyone currently using an oral and/or topical prescription acne treatment. Anyone unwilling to stop using their current acne supplements. Anyone with known severe allergic reactions. Anyone unwilling to avoid excessive sun exposure. Anyone who is breastfeeding, pregnant, or attempting to become pregnant. Anyone unwilling to follow the study protocol. Anyone who identifies as having sensitive skin.

05

Study design

Phase
Not applicable
Primary purpose
Other
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
40 participants (actual)

Study arms

  • Experimental
    Test arm: Acne Serum

    Participants will use the serum after cleansing and toning every morning for 8 weeks (56 days).

    Other: Rael Miracle Clear Complete Acne Serum

Interventions

  • OtherRael Miracle Clear Complete Acne Serum

    This acne serum contains the following ingredients: 1.5% Salicylic acid. 2% Niacinamide. 0.5% Zinc Pyrrolidone Carboxylic Acid (PCA). Hyaluronic Acid.

06

What researchers measure

Primary outcomes

  1. Changes in the appearance of facial acne. [Timeframe: Baseline to Day 56]

    Before and after photos will undergo virtual skin grading by a board-certified dermatologist to assess this change. Participants will also complete questionnaires rating the appearance of their facial acne. Questionnaires will use a 5-point Likert scale, with 0 indicating the less favourable response and 5 indicating the most favourable response.

    Time frame: 56 days

  2. Changes in the appearance of post-acne pigmentation. [Timeframe: Baseline to Day 56]

    Before and after photos will undergo virtual skin grading by a board-certified dermatologist to assess this change. Participants will also complete questionnaires rating the appearance of their post-acne pigmentation. Questionnaires will use a 5-point Likert scale, with 0 indicating the less favourable response and 5 indicating the most favourable response.

    Time frame: 56 days

Secondary outcomes

  1. Changes in facial skin hydration. [Timeframe: Baseline to Day 56]

    Before and after photos will undergo virtual skin grading by a board-certified dermatologist to assess this change. Participants will also complete questionnaires rating their perception of facial skin hydration. Questionnaires will use a 5-point Likert scale, with 0 indicating the less favourable response and 5 indicating the most favourable response.

    Time frame: 56 days

  2. Changes in facial skin softness. [Timeframe: Baseline to Day 56]

    Participants will complete questionnaires rating their perception of facial skin softness. Questionnaires will use a 5-point Likert scale, with 0 indicating the less favourable response and 5 indicating the most favourable response.

    Time frame: 56 days

  3. Changes in facial skin texture. [Timeframe: Baseline to Day 56]

    Before and after photos will undergo virtual skin grading by a board-certified dermatologist to assess this change. Participants will also complete questionnaires rating their perception of facial skin texture. Questionnaires will use a 5-point Likert scale, with 0 indicating the less favourable response and 5 indicating the most favourable response.

    Time frame: 56 days

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Study locations

1 site
  • Citruslabs
    Santa Monica, California 90404, United States
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References and documents

Individual participant data

Plan to share: Undecided

No publications or documents are linked to this record.

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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Aug 23, 2024, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT06120452
Lead sponsor
Rael
Collaborators
Citruslabs
Responsible party
Sponsor
First posted
Nov 7, 2023
Start date
Oct 6, 2023
Primary completion
Jan 31, 2024
Completion
Jan 31, 2024
Last update
Aug 23, 2024

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Aug 2024. You cannot join it, but the record below documents what was studied.

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