An observational study in Ischemic Stroke, sponsored by China Medical University Hospital. Completed at 1 site in Taiwan. Open to participants aged 20 Years and older. Per ClinicalTrials.gov, last updated 2023-10-24.
Sponsored by China Medical University Hospital · Observational
In the high-stakes battle against ischemic cerebrovascular disease, where every second counts and the margin for error is slim, how do the investigators tip the scales in favor of patient survival and improved outcomes? This groundbreaking study, the first nationwide, population-based analysis with long-term follow-up in an Asian context, dives deep into this critical question. Leveraging an expansive dataset from Taiwan's National Health Insurance Research Database, the investigators scrutinize the efficacy and risks of aggressive surgical interventions-specifically, EC-IC bypass, CEA, and CAS-in a cohort of over 84,000 patients.
This paper serves as a milestone, bridging the gap between medical idealism and clinical reality. It calls for a surgical renaissance, emphasizing the need for refining techniques and enhancing patient selection protocols. If participants're looking for a comprehensive, nuanced, and, above all, actionable insight into the surgical treatment of ischemic cerebrovascular disease, this is the study that could redefine the paradigm.
2,595 studies on the registry are indexed under Ischemic Stroke; 932 are open to participants now.
This study's enrollment of 204,411 is above the median of 300 across 777 observational studies indexed under Ischemic Stroke.
Browse Ischemic Stroke studies →China Medical University Hospital is the lead sponsor of 464 studies on the registry; 116 are open to participants now.
Counted across the registry records on this site, refreshed daily.
The cohort comprises all inpatients hospitalized between January 1, 2001, and December 31, 2010, diagnosed with a first stenosis-occlusion ischemic stroke (ICD-9-CM codes 433-434). All participants underwent either a computed tomography (CT) scan or magnetic resonance imaging (MRI) within two days before or after hospital admission.
The date of the first ischemic stroke hospitalization served as the index event.
Among these patients, those who underwent surgical interventions post-hospitalization were categorized into three distinct groups: CEA (ICD-9-CM code 3812), CAS (ICD-9-CM code 3990), and EC-IC (ICD-9-CM code 3928), with the operation date being the index date.
Those who did not receive any surgical interventions were considered the non-intervention control group and had their first hospitalization date as the index date.
Exclusion Criteria:
rehospitalization
rehospitalization due to ischemic or hemorrhagic stroke
Time frame: Follow-up assessments were planned at 3 months, 6 months, 1 year, 2 years, and 3 years post-index date
Cardiac events
congestive heart failure and acute myocardial infarction were also monitored throughout the study period.
Time frame: Follow-up assessments were planned at 3 months, 6 months, 1 year, 2 years, and 3 years post-index date
This study is completed, as verified in Oct 2023. You cannot join it, but the record below documents what was studied.
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China Medical University Hospital