An interventional study of Omitting of usage of intraabdominal drains after repair of peptic ulcer perforations and Using intraabdominal drains in Peptic Ulcer Perforations, sponsored by Cairo University. Completed at 1 site in Egypt. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2025-08-26.
Sponsored by Cairo University · Not applicable, Interventional, and Treatment
. This study aimed to evaluate ERAS application outcomes via omitting the intraabdominal drains compared to regular using of the drains in patients undergoing perforated duodenal ulcer repairs in emergency abdominal surgeries.
Patients will be randomly assigned into two groups. In Group A : the investigators will put intraabdominal drains, and in Group ,thd investigators will not put any intraabdominal drains. Our primary outcomes will be hospital stayl engthand pain score;Data analysis packages will be SPSS version 21 Qualitative data will be presented by number and percentage, quantitative data by mean, standard deviation, median and interquartile range.
21 studies on the registry are indexed under Peptic Ulcer Perforation; 4 are open to participants now.
This study's enrollment of 100 is above the median of 66 across 16 interventional studies indexed under Peptic Ulcer Perforation.
Browse Peptic Ulcer Perforation studies →Cairo University is the lead sponsor of 4,941 studies on the registry; 1,458 are open to participants now.
Of its 37 completed or terminated interventional studies of FDA-regulated products, 5 (14%) have results posted.
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Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
- Patients older than 18 years with perforated peptic ulcer who underwent exploratory laparotomy or laparoscopy and repair with omental pedicle techniques will included in the study.
Exclusion Criteria:
preoperative shock on admission.
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
A weakened immune system. It can come from an illness, such as HIV or some blood cancers, or from medicines that turn the immune system down, for example after an organ transplant or for an autoimmune disease; steroids at higher doses count.
Read whether the line is about a condition or about medicines, and which medicines and doses it means.
Anti-inflammatory medicines such as prednisone, prednisolone and dexamethasone — not the anabolic steroids used for muscle.
Studies differ in what they allow: check which steroid medicines, routes (tablets, injections, creams, inhalers, eye drops) and doses this study accepts.
The human immunodeficiency virus, which weakens the immune system.
Many studies now accept people whose HIV is controlled on treatment, judged by the viral load and the CD4 count. Check the limits this study sets.
The anaesthetists’ scale of health before surgery: I is healthy, II has a mild illness that is under control, III a severe one, IV a severe illness that is a constant threat to life. V and VI are used for the critically ill and for organ donors.
Immunosuppression
A weakened immune system. It can come from an illness, such as HIV or some blood cancers, or from medicines that turn the immune system down, for example after an organ transplant or for an autoimmune disease; steroids at higher doses count.
Read whether the line is about a condition or about medicines, and which medicines and doses it means.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Corticosteroids (steroids)
Anti-inflammatory medicines such as prednisone, prednisolone and dexamethasone — not the anabolic steroids used for muscle.
Studies differ in what they allow: check which steroid medicines, routes (tablets, injections, creams, inhalers, eye drops) and doses this study accepts.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
HIV
The human immunodeficiency virus, which weakens the immune system.
Many studies now accept people whose HIV is controlled on treatment, judged by the viral load and the CD4 count. Check the limits this study sets.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
ASA physical status
The anaesthetists’ scale of health before surgery: I is healthy, II has a mild illness that is under control, III a severe one, IV a severe illness that is a constant threat to life. V and VI are used for the critically ill and for organ donors.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
In Group A the investigators will put intraabdominal drains
Other: Using intraabdominal drains
The investigators will not put any intraabdominal drains
Other: Omitting of usage of intraabdominal drains after repair of peptic ulcer perforations
omitting the intraabdominal drains
The investigators will put intraabdominal drains
number of days of hospital stay
hospital stay length
Time frame: Up to 30 days
number of patients with infection-related postoperative complications such as superficial, deep or organ space SSI, hospital acquired pneumonia
number of patients with infection-related postoperative complications such as superficial, deep or organ space SSI, hospital acquired pneumonia
Time frame: 30 days
incidence of Post operative repair leak
incidence of Post operative repair leak
Time frame: 30 days
number of days before frist bowel motion
number of days before frist bowel motion
Time frame: 7 days
severity of operative pain measured by Visual Analogue Scale (VAS
from 1 to 10 1 indicated minimum pain and 10 maximum pain
Time frame: 7 days
INCIDENCE OF postoperative nausea and vomiting (PONAV
INCIDENCE OF postoperative nausea and vomiting (PONAV
Time frame: 7 days
Plan to share: No
Ran from Mar 2023 to primary completion in Feb 2024, 11 months.
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This study is completed, as verified in Aug 2025. You cannot join it, but the record below documents what was studied.
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