ClinicalTrials.gg
RecruitingNCT06080633Updated Jun 13, 2024

Facial Prediction Technology for Edentulous Patients

An observational study in Edentulous Jaw, sponsored by KU Leuven. Recruiting at 1 site in Belgium. Open to participants aged 50 Years to 100 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2024-06-13.

Sponsored by KU Leuven · Observational

From the registry’s dates

  • Primary completion was expected by Dec 2025, 10 months ago, but the record still lists the study as recruiting.
  • Started Jun 2023; still recruiting 3 years 4 months later.
Study type
Observational
Model
Case-only
Time perspective
Retrospective
Enrollment
24
Ages
50 Years to 100 Years
Sex
All
01

Study summary

According to data from the World Health Organization, approximately 160 million people worldwide are edentulous. The incidence increases with age, and the proportion of edentulous patients is higher in the population aged 60 and above. Loss of teeth or edentulism can affect facial appearance, causing people to feel self-conscious and loss confidence in social situations, and even lead to psychological illnesses. Therefore, edentulous patients not only pay close attention to the recovery of oral function but also attach great importance to facial contour improvement. For a long time, due to technological limitations, clinicians have been unable to depict the changes in facial contour after implant placement for patients before surgery. However, with the development of artificial intelligence technology, deep learning-based methods for predicting soft tissue facial deformation have made this mission a possibility. This study established a multi-modal dataset for edentulous patients before and after implant restoration to lay the foundation for predicting facial contour changes after implant treatment. A graph generative adversarial network based on multi-modal data was proposed to achieve fast and high-precision facial contour prediction. To address the common challenges of slow computation and excessive computational resource consumption in current triangular mesh deformation simulation methods, this project innovatively proposed a graph generative adversarial network that uses multi-modal data and incorporates self-attention mechanisms to achieve fast and high-precision facial contour prediction for edentulous patients after implant restoration.

02

Conditions studied

  • Edentulous Jaw

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Keywords

  • Edentulous Jaw
  • deep learning
  • oral implantology
  • facial prediction
03

In context

Jaw, Edentulous

175 studies on the registry are indexed under Jaw, Edentulous; 24 are open to participants now.

This study's planned enrollment of 24 is below the median of 40 across 27 observational studies indexed under Jaw, Edentulous.

Browse Jaw, Edentulous studies →

Lead sponsor

KU Leuven is the lead sponsor of 371 studies on the registry; 63 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
50 Years to 100 Years
Sexes eligible
All
Accepts healthy volunteers
Yes
Sampling method
Probability sample

Study population

Patient with Edentulous Maxilla after Implant Prosthetic Restoration

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Patients with complete edentulism,
  • aged 50 years or above,
  • in good physical health,

Exclusion criteria

Exclusion Criteria:

  • patients who refuse to participate in the study,
  • patients who cannot undergo facial scanning.
05

Study design

Observational model
Case-only
Time perspective
Retrospective
Enrollment
24 participants (estimated)
Patient registry
No
06

What researchers measure

Primary outcomes

  1. Changes in Soft Tissue Volume in the Lip Region after Implant Dentistry

    Quantitative analysis of lip volume changes in patients after oral implant surgery using facial scanning equipment

    Time frame: Between pre-operation and after Implant-Supported Fixed Prostheses up to 3 months

07

Study locations

1 of 1 sites recruiting
08

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reached

Started Jun 2023 (actual). Primary completion is estimated for Dec 2025, 30 months after the start.

How these figures are worked out, and which studies are left out of them.

Registered
Aug 29, 2023
First posted
Oct 12, 2023
StartActual
Jun 1, 2023
Primary completionEst.
Dec 1, 2025
CompletionEst.
Dec 1, 2026
Last update
Jun 13, 2024
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Jun 13, 2024, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT06080633
Lead sponsor
KU Leuven
Responsible party
Hongyang Ma (Research Associate, KU Leuven) — Principal investigator
First posted
Oct 12, 2023
Start date
Jun 1, 2023
Primary completion
Dec 1, 2025 (estimated)
Completion
Dec 1, 2026 (estimated)
Last update
Jun 13, 2024

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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No contact was published for this record. The registry link below has the sponsor’s details.

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