Development of a Digital Personalised Nutrition Tool for Adolescents Undergoing Cancer Treatment

Browse trials for

• Child Nutrition Disorders 164
• Neoplasms 9,365

Keywords

• adolescent
• cancer
• personalised nutrition
• mHealth
• Digital health
• experience sampling method

Child Nutrition Disorders

164 studies on the registry are indexed under Child Nutrition Disorders; 34 are open to participants now.

This study's planned enrollment of 30 is below the median of 428 across 130 interventional studies indexed under Child Nutrition Disorders.

Lead sponsor

KU Leuven is the lead sponsor of 359 studies on the registry; 63 are open to participants now.

Study arms

• Experimental
  Phase 2: MybYte digital personalised nutrition tool

  Other: The MybYte tool, a digital personalised nutrition tool for adolescents undergoing cancer treatment

Interventions

• OtherThe MybYte tool, a digital personalised nutrition tool for adolescents undergoing cancer treatment

  In Phase 2, a feasibility and acceptability study, all participants will use MybYte for 7 days each month over 6 months. Using experience sampling methodology (ESM), the tool sends 3-5 brief prompts per day about dietary intake, treatment-related symptoms and side effects, appetite, and taste preferences. Based on their responses, participants receive immediate, targeted nutrition tips. Once a month, researchers will integrate body composition and dietary intake data to provide more personalised nutrition feedback and advice. The tool is primarily a health communication tool.

Primary outcomes

1. The MybYte tool

   Phase 1: Final version of MybYte, a digital personalised nutrition tool for adolescents undergoing cancer treatment

   Time frame: From the time of enrollment into phase 1 until month 8

2. Feasibility (%)

   Phase 2: Feasibility of the MybYte tool determined by engagement (%), recruitment (%), and retention (%)

   Time frame: From enrollment into phase 2 until end of month 6

3. Acceptability (5 point response scale)

   Phase 2: Acceptability of the MybYte tool will be determined by questionnaire at month 3 and 6, including a 5 point response scale to the following categories: engagement, functionality, aesthetics, content, relevance, interference, quality, and perceived impact.

   Time frame: From enrollment into phase 2 until end of month 6

Secondary outcomes

1. Adolescent perspectives of nutrition during cancer treatment

   Phase 1: Thematic analysis of semi-structured interviews exploring adolescents' lived experiences regarding nutrition, nutritional status, and nutrition communication during cancer treatment

   Time frame: From enrollment into phase 1 to end of month one

2. Fat mass (kg)

   Phase 2: Fat mass (kg) measured monthly by the Bodystat Multiscan 5000 bioelectrical impedance spectroscopy

   Time frame: From enrollment into phase 2 to the end of month 6

3. Fat free mass (kg)

   Phase 2: Fat free mass (kg) measured monthly by the Bodystat Multiscan 5000 bioelectrical impedance spectroscopy

   Time frame: From enrollment into phase 2 until end of month 6

4. Skeletal muscle mass (kg)

   Phase 2: skeletal muscle mass (kg) measured monthly by the Bodystat Multiscan 5000 bioelectrical impedance spectroscopy

   Time frame: From the time on enrollment into phase 2 until the end of month 6

5. Phase angle (degrees)

   Phase 2: Phase angle (degrees) measured monthly by the Bodystat Multiscan 5000 bioelectrical impedance spectroscopy

   Time frame: From enrollment into phase 2 until the end of month 6

6. Body mass index (kg/m^2)

   Phase 2: Body mass index. weight (kg) and height (m) will be combined to report BMI in kg/m\^2.

   Time frame: From enrollment into phase 2 until the end of month 6.

7. Resting energy metabolism (kcal/day)

   Phase 2: Resting energy metabolism (kcal/day) measured monthly via the Bodystat Multiscan 5000 bioelectrical impedance spectroscopy and at diagnosis, month 3, and month 6 using indirect calorimetry.

   Time frame: From enrollment into phase 2 to end of month 6.

8. Generic health- related quality of life (5 point response scale)

   Phase 2: Health- related quality of life at diagnosis, months 3, and 6 using the PedsQL 4.0. Items are rated on a 5-point response scale ranging from 0 (never a problem) to 4 (almost always a problem)

   Time frame: From enrollment into phase 2 to the end of month 6

9. Cancer specific health-related quality of life (5 point response scale)

   Phase 2: Cancer specific health-related quality of life measured at diagnosis, month 3, and month 6 by the PedsQL 3.0 Cancer Module. Items are rated on a 5-point response scale ranging from 0 (never a problem) to 4 (almost always a problem)

   Time frame: From enrollment into phase 2 until the end of month 6

10. Macronutrient dietary intake (g/day)

    Phase 2: Protein, fat, and carbohydrate intake (g/day), measured over 7 days per month for 6 months using the MybYte tool.

    Time frame: From enrollment into phase 2 to the end of month 6.

11. Dietary food group intake (g/day)

    Phase 2: Dietary food group intake (g/day), measured over 7 days per month for 6 months using the MybYte tool.

    Time frame: From enrollment into phase 2 until the end of month 6

Study documents

• Study protocol · Jul 16, 2026

Documents are hosted by the registry — open the source record to download them.

Individual participant data

Plan to share: No — Individual participant data will not be shared with other researchers because the study involves a small number of adolescent participants and collects sensitive health-related data, which could increase the risk of participant re-identification. Study findings will be reported in accordance with applicable privacy and data-protection requirements.