A Phase 1 interventional study of silk fibroin and Chlorhexidin in Periodontal Pocket, sponsored by Krishnadevaraya College of Dental Sciences & Hospital. Not yet recruiting. Open to participants aged 30 Years to 50 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2023-09-22.
Sponsored by Krishnadevaraya College of Dental Sciences & Hospital · Phase 1, Interventional, and Treatment
The current study is a prospective randomised split mouth study to evaluate the effect of Silk fibroin as drug delivery system while simultaneously assessing the efficacy of silk fibroin in comparison to chlorhexidine.
Fifteen healthy individuals satisfying the inclusion and exclusion criteria were recruited for the study. A detailed, thorough medical and dental history was obtained and each patient was subjected to comprehensive clinical and radiological examination. All patients were informed about the nature of the study, procedure involved, potential benefits and risks associated with procedure and written informed consent were obtained from all patients.All the patients underwent scaling and root planing.
Following randomization, the site will be assigned to one of the three study groups.
126 studies on the registry are indexed under Periodontal Pocket; 36 are open to participants now.
This study's planned enrollment of 15 is below the median of 30 across 109 interventional studies indexed under Periodontal Pocket.
Browse Periodontal Pocket studies →Krishnadevaraya College of Dental Sciences & Hospital is the lead sponsor of 51 studies on the registry; 13 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
test group 1 is treated with silk fibroin
Biological: silk fibroin
test group 2 is treated with chlorhexidine
Drug: Chlorhexidin
test group 3 is treated with combination of silk fibroin and chlorhexidine
Biological: combination of silk fibroin and chlorhexidine
silk fibroin extracted from bombyx mori silk worm is processed in laboratory to form silk fibroin films
chlorhexidine is used
Also known as: chlorhexidine
combination of silk fibroin and chlorhexidine is used
Probing pocket Depth (PPD)
measured using a UNC-15 probe (university of North Carolina-15 periodontal probe- Hu-Friedy, Chicago, IL, USA
Time frame: 3 months
Relative attachment level (RAL)
measured by placing the acrylic stent on the selected teeth using UNC-15 probe (university of North Carolina-15 periodontal probe- Hu-Friedy, Chicago, IL, USA)
Time frame: 3 months
Plaque Index
measured on the tooth surface using a probe
Time frame: 3 months
Gingival index
measured on the tooth surface using a probe
Time frame: 3 month
Modified Sulcus Bleeding Index
measured on the tooth surface using a probe
Time frame: 3 months
No study locations are listed for this record.
This study is not yet recruiting, as verified in Sep 2023. You cannot join it, but the record below documents what was studied.
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Krishnadevaraya College of Dental Sciences & Hospital