An observational study in Cardiovascular Diseases in Pregnancy, sponsored by National Institute of Cardiovascular Diseases, Pakistan. Recruiting at 1 site in Pakistan. Open to female participants. Per ClinicalTrials.gov, last updated 2023-08-30.
Sponsored by National Institute of Cardiovascular Diseases, Pakistan · Observational
Consecutive obstetric patients attending routine antenatal visits were enrolled in this ongoing registry. A standardized 2D transthoracic echocardiogram (TTE) protocol was employed. Ejection fraction (EF) was quantified using biplane Simpson's method.
Consecutive obstetric patients attending routine antenatal visits were enrolled in this ongoing registry. A standardized 2D transthoracic echocardiogram (TTE) protocol was employed, including parasternal long and short, apical 4- and 2-chamber views. Continuous wave and pulse wave Doppler were used to assess left ventricular outflow tract (LVOT) gradients. Left ventricular (LV) function was quantified using biplane Simpson's method and visually assessed by two independent readers. Patients with significant valve disease or congenital heart disease underwent complete TTE. Those diagnosed with LV dysfunction or other cardiovascular diseases (CVD) were referred to the Cardio-Obstetrics clinic for further management and long-term follow-up.
4,904 studies on the registry are indexed under Cardiovascular Diseases; 919 are open to participants now.
This study's planned enrollment of 10,000 is above the median of 573 across 1,485 observational studies indexed under Cardiovascular Diseases.
Browse Cardiovascular Diseases studies →National Institute of Cardiovascular Diseases, Pakistan is the lead sponsor of 22 studies on the registry; 13 are open to participants now.
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Consecutive obstetric patients attending routine antenatal visits
Exclusion Criteria:
Number of participants found to have abnormal left ventricular function
Prevalence of Left ventricular dysfunction (Ejection Fraction\<55%)
Time frame: At the time of screening echocardiogram
Number of participants found to have abnormal heart valve function
Structural heart abnormalities (valvular heart lesions classified as mild, moderate and severe)
Time frame: At the time of screening echocardiogram
Number of participants found to have adverse Maternal outcomes
Maternal Mortality, Cardiogenic shock
Time frame: At the time of delivery
Number of participants found to have adverse Fetal outcomes
Infant Mortality, Infant birth weight (kg)
Time frame: At the time of delivery
Plan to share: No
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National Institute of Cardiovascular Diseases, Pakistan