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CompletedNCT05959798Updated Jul 25, 2023

High Power Short Duration Ablation Compared to Moderate Power Long Duration Ablation for Pulmonary Vein Isolation

An observational study in Paroxysmal Atrial Fibrillation, sponsored by Deutsches Herzzentrum Muenchen. Completed at 1 site in Germany. Open to participants aged 18 Years to 80 Years. Per ClinicalTrials.gov, last updated 2023-07-25.

Sponsored by Deutsches Herzzentrum Muenchen · Observational

Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
204
Ages
18 Years to 80 Years
Sex
All
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Study summary

High Power Short Duration Ablation Compared to Moderate Power Long Duration Ablation for Pulmonary Vein Isolation: safety and acute procedural outcome

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Conditions studied

  • Paroxysmal Atrial Fibrillation

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03

In context

Atrial Fibrillation

3,870 studies on the registry are indexed under Atrial Fibrillation; 924 are open to participants now.

This study's enrollment of 204 is below the median of 300 across 1,363 observational studies indexed under Atrial Fibrillation.

Browse Atrial Fibrillation studies →

Lead sponsor

Deutsches Herzzentrum Muenchen is the lead sponsor of 112 studies on the registry; 10 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years to 80 Years
Sexes eligible
All
Sampling method
Probability sample

Study population

Patients with documented paroxysmal atrial fibrillation, not previously treated by left atrial catheter ablation

Inclusion criteria

  • symptomatic, documented, drug-resistent paroxysmal atrial fibrillation
  • effective oral anticoagulation

Exclusion criteria

Exclusion Criteria:

  • any prior left atrial ablation procedure
  • presence of left atrial thrombus
  • secondary atrial fibrillation due to electrolyte imbalance or thyroid disease
  • any prior oesophageal or gastric surgery
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Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
204 participants (actual)
Patient registry
No

Groups and cohorts

  • High power short duration ablation

    Procedure: High power short duration ablation

  • Moderate power long duration ablation

    Procedure: High power short duration ablation

Interventions

  • ProcedureHigh power short duration ablation

    Pulmonary vein isolation by high power short duration radiofrequency catheter ablation

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What researchers measure

Primary outcomes

  1. Number of reconnected pulmonary veins 20 minutes after ablation in comparison of both ablation groups

    Time frame: Acute endpoint

Secondary outcomes

  1. Time to first documented recurrence of atrial fibrillation after a 6-week blanking period.

    Time frame: 12 months after ablation

07

Study locations

1 site
  • Deutsches Herzzentrum München
    München, 80636, Germany
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References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jul 25, 2023, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT05959798
Lead sponsor
Deutsches Herzzentrum Muenchen
Responsible party
Sponsor
First posted
Jul 25, 2023
Start date
Apr 20, 2019
Primary completion
Jul 17, 2023
Completion
Jul 17, 2023
Last update
Jul 25, 2023

Study contacts

Isabel Deisenhofer, Prof. Dr.
principal investigator · Deutsches Herzzentrum München, Abt. für Elektrophysiologie

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Jul 2023. You cannot join it, but the record below documents what was studied.

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