An interventional study of Dexamethasone 4mg in Common Bile Duct Diseases, Common Bile Duct Calculi and Common Bile Duct Stricture, sponsored by Gujranwala medical college District Headquarters Hospital, Gujranwala. Completed at 1 site in Pakistan. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2025-03-21.
Sponsored by Gujranwala medical college District Headquarters Hospital, Gujranwala · Not applicable, Interventional, and Treatment
The main aim of this clinical trial is to evaluate the effects of dexamethasone on common bile duct cannulation time during endoscopic retrograde cholangiopancreatography (ERCP) in patients with biliary pathologies. The study will also study the effects of dexamethasone on total procedure time and total fluoroscopy time during ERCP.
Participants will be divided into two groups, treatment group and placebo group. Patients in treatment group will receive dexamethasone and those in placebo group will be given normal saline before undergoing ERCP. The results in both groups will be compared to determine the effects of dexamethasone.
199 studies on the registry are indexed under Gallstones; 35 are open to participants now.
This study's enrollment of 80 is below the median of 98 across 121 interventional studies indexed under Gallstones.
Browse Gallstones studies →Gujranwala medical college District Headquarters Hospital, Gujranwala is the lead sponsor of 4 studies on the registry; 2 are open to participants now.
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Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Anti-inflammatory medicines such as prednisone, prednisolone and dexamethasone — not the anabolic steroids used for muscle.
Studies differ in what they allow: check which steroid medicines, routes (tablets, injections, creams, inhalers, eye drops) and doses this study accepts.
Corticosteroids (steroids)
Anti-inflammatory medicines such as prednisone, prednisolone and dexamethasone — not the anabolic steroids used for muscle.
Studies differ in what they allow: check which steroid medicines, routes (tablets, injections, creams, inhalers, eye drops) and doses this study accepts.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Experimental arm patients will be receiving 2 ml (4mg) of dexamenthasone prior to undergoing ERCP.
Drug: Dexamethasone 4mg
Placebo arm patients will be receiving 2 ml of normal saline prior to undergoing ERCP.
Drug: Dexamethasone 4mg
An injection of 4mg of dexamethasone will be given to patients approximately 2 to 4 hours prior to the procedure of ERCP.
Also known as: steroids
Shortening of CBD cannulation time
To determine the effects of dexamethasone on shortening of CBD cannulation time
Time frame: CBD cannulation time will be calculated from the start of the procedure (0 minutes) till complete CBD cannulation has been achieved through catheter and confirmed by fluoroscopy or procedure abandoned if unsuccessful cannulation by 30 minutes.
Plan to share: No
Ran from Aug 2023 to primary completion in Apr 2024, 8 months.
Of 58 non-industry interventional studies with no phase under Gallstones, half reached primary completion within 20 months of starting (the median), counting those still running; a quarter within 12 and three quarters within 43. This study's 8 months is below that.
Counting every sponsor, half of 58 studies reached it within 20 months; a quarter within 12 and three quarters within 43.
How these figures are worked out, and which studies are left out of them.
This study is completed, as verified in Mar 2025. You cannot join it, but the record below documents what was studied.
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Studies of the drug tested here: Dexamethasone
Gujranwala medical college District Headquarters Hospital, Gujranwala