An interventional study of BP REACH Intervention in Myocardial Infarction, Hypertension and Stroke, sponsored by University of Southern California. Active, not recruiting at 4 sites in United States. Open to participants aged 35 Years and older. Per ClinicalTrials.gov, last updated 2026-09-14.
Sponsored by University of Southern California · Not applicable, Interventional, and Prevention
BP-REACH is a study of a team-based (pharmacist and health coach) program for lowering blood pressure for people with a prior stroke or heart attack in the Los Angeles Department of Health Services healthcare system.
The goal of this clinical trial is to test if this team based program is better at helping people reduce their blood pressure than usual care for people with prior heart attack or stroke. The main questions it aims to answer are:
Hypertension is the leading contributor to preventable death and a major risk factor for recurrent cardiovascular events. To enhance BP control after stroke or myocardial infarction (MI), multilevel interventions are needed that incorporate health system and patient level factors.
BP-REACH aims to test the impact of an intervention on systolic blood pressure (SBP) for individuals with a history of stroke or MI in a randomized controlled trial in the Los Angeles Department of Health Services healthcare system. The primary outcome will be change in systolic blood pressure (SBP) at 12 months.
Hypothesis: Patients randomized to the intervention will achieve >2.4 mm Hg greater reduction in SBP at 1 year versus those randomized to usual care.
The study population will include participants from the inpatient and outpatient settings in Los Angeles County Department of Health Services health centers. The participants will be randomized in a 1:1 fashion to usual care or intervention, stratified by site, language and cardiovascular event (myocardial infarction, stroke). Outcomes will be collected from all participants at Baseline, 3 month and 12 month timepoints. The primary outcome is SBP.
Participants randomized to the intervention arm will receive additional a home blood pressure monitor, monthly phone calls from a health coach, and medication initiation and titration by a clinical pharmacist. The pharmacist will follow Los Angeles County Department of Health Services expected practices, which align with the ACC/AHA guidelines for blood pressure control and AHA guidelines for Secondary Stroke Prevention.
2,744 studies on the registry are indexed under Myocardial Infarction; 418 are open to participants now.
This study's planned enrollment of 546 is above the median of 148 across 1,595 interventional studies indexed under Myocardial Infarction.
Browse Myocardial Infarction studies →University of Southern California is the lead sponsor of 773 studies on the registry; 135 are open to participants now.
Of its 68 completed or terminated interventional studies of FDA-regulated products, 32 (47%) have results posted.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Participants receive the usual care received by patients of the medical center
Participants follow the intervention protocol, including receiving educational materials, a home blood pressure monitor, coaching calls from BP REACH coaches and medication management from a pharmacist.
Behavioral: BP REACH Intervention
Educational materials, written and digital. Home blood pressure monitor and self management education from BP REACH coach. Monthly coaching calls from BP REACH coach. Medication management by pharmacist
Systolic blood pressure (SBP) mmHG
Collected by study staff using blood pressure monitor
Time frame: 12 months
Life's Essential 8
American Heart Association - survey measure. Score of 0-100, with 100 indicating a perfect score for cardiovascular health
Time frame: 12 months
BMI (body mass index)
Height (cm) and weight (kg) collected by study staff, height divided by height indicating percentage of fat on the body
Time frame: 12 months
Total cholesterol
Lab collection by study staff
Time frame: 12 months
HgbA1c (hemoglobin A1C)
Lab collection by study staff
Time frame: 12 months
Diet
Survey - California Health Interview Survey
Time frame: 12 months
Physical activities
Survey - Behavioral Risk Factor Surveillance System Survey Questionnaire
Time frame: 12 months
Smoking
Survey - PATH wave 1 survey
Time frame: 12 months
Plan to share: No
No publications or documents are linked to this record.
This study is active, not recruiting, as verified in Sep 2026. You cannot join it, but the record below documents what was studied.
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University of Southern California