An observational study in Thyroid Diseases, sponsored by Sohag University. Enrolling by invitation at 1 site in Egypt. Open to participants aged 16 Years and older. Per ClinicalTrials.gov, last updated 2023-07-05.
Sponsored by Sohag University · Observational
the study aimed at evaluating efficacy of auto-transplantation of thyroid tissue after total thyroidectomy in benign thyroid disorders to keep the patient euthyroid with no need for life long hormone replacement therapy.
This study will be a prospective study which will be conducted at Sohag University Hospital after approval of the protocol the study population include . Adult patients with goiters are seen in the general surgery outpatient clinic The study included thirty studied cases presented in the outpatient clinic with benign thyroid disorders for whom total thyroidectomy was performed
967 studies on the registry are indexed under Thyroid Diseases; 197 are open to participants now.
This study's planned enrollment of 30 is below the median of 150 across 381 observational studies indexed under Thyroid Diseases.
Browse Thyroid Diseases studies →Sohag University is the lead sponsor of 1,183 studies on the registry; 612 are open to participants now.
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Adult patients with benign multi nodular goiter
Exclusion Criteria:
Procedure: total thyroidectomy followed by thyroid auto transplantation
All studied cases received general endotracheal anaesthesia, and all underwent total thyroidectomy. Frozen section will be done intraoperative to exclude malignancy and obtain piece of healthy tissue part . Most healthy-looking part of gland was selected after complete excision. Thyroid tissue to be transplanted weighed between two and five grammes. This section was finely split into ten-fifteen fragments with scalpel. Small pocket was created in sternomastoid muscle, into which these minor fragments were implanted, and this pocket was closed with absorbable sutures to prevent displacement of implanted fragments and was marked with metallic stables, as well as good hemostasis of thyroid bed and skin was closed with subcuticular sutures using absorbable three-zero Vicryl sutures.
Thyroid function following thyroid auto transplantation after total thyroidectomy
Thyroid hormone levels will be assessed after auto transplantation of thyroid tissue from benign thyroid patients following total thyroidectomy
Time frame: six months
Plan to share: No
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Sohag University