An interventional study of Fluid therapy under the guide of Carotid ultrasound in Hypotension on Induction, sponsored by Min Su. Recruiting at 1 site in China. Open to participants aged 60 Years to 80 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2023-06-13.
Sponsored by Min Su · Not applicable, Interventional, and Prevention
The goal of this clinical trial is to learn about Whether carotid ultrasound guided fluid management can reduce the incidence of hypotension after general anesthesia induction in elderly patients undergoing gastrointestinal surgery.
The main question[s] it aims to answer are:
Whether fluid therapy reduces the incidence of general anaesthesia induced hypotension in elderly patients undergoing gastrointestinal surgery.
Whether carotid ultrasound can guide fluid management in elderly patients undergoing gastrointestinal surgery.
Participants will use carotid ultrasound to assess volume status. If volume is insufficient, fluid therapy will be selected until volume is sufficient, anesthesia will be then induced. If volume is sufficient, anesthesia will be directly induced. There is a comparison group: No carotid ultrasound will be used to assess the volume status of the patients, and anesthesia will be directly induced.
1,003 studies on the registry are indexed under Hypotension; 173 are open to participants now.
This study's planned enrollment of 150 is above the median of 80 across 675 interventional studies indexed under Hypotension.
Browse Hypotension studies →Min Su is the lead sponsor of 12 studies on the registry; 9 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Participants will use carotid ultrasound to assess volume status. If volume is insufficient, fluid therapy will be selected until volume is sufficient, anesthesia will be then induced. If volume is sufficient, anesthesia will be directly induced.
Other: Fluid therapy under the guide of Carotid ultrasound
No carotid ultrasound will be used to assess the volume status of the patients, and anesthesia will be directly induced.
Participants will use carotid ultrasound to assess volume status. If volume is insufficient, fluid therapy will be selected until volume is sufficient. If volume is sufficient, no fluid therapy will be given.
Occurrence of hypotension after anesthesia induction
Hypotension occurred from anesthesia induction to 20 minutes after induction in both groups.
Time frame: General anesthesia induction from the beginning to 20 minutes after induction
Postoperative acute kidney injury
Postoperative creatinine increased for a short period of time to more than 0.3mg/dl (26.5μmol/L) or to more than 1.5 times the preoperative creatinine concentration.
Time frame: Within 7 days after surgery
postoperative delirium
Newly diagnosed delirium by the psychiatric department within 30 days after surgery
Time frame: Within 30 days after surgery
postoperative stroke
Any newly diagnosed postoperative neurological dysfunction within 30 days after surgery.
Time frame: Within 30 days after surgery
Eligibility is decided by the study team. Share this record with your doctor or contact the team directly.
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