ClinicalTrials.gg
RecruitingNCT05863962Updated May 18, 2023

Comparative Effects of Jacobson's Relaxation Techniques and Stretching Exercises in Preeclampsia

An interventional study of walking and Stretching and walking and Jacobsons relaxation technique in Pre-Eclampsia; Complicating Pregnancy, sponsored by Riphah International University. Recruiting at 1 site in Pakistan. Open to female participants aged 25 Years to 35 Years. Per ClinicalTrials.gov, last updated 2023-05-18.

Sponsored by Riphah International University · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Primary completion was expected by Jul 2023, 3 years 4 months ago, but the record still lists the study as recruiting.
  • Registered 4 months after the study started (first participant enrolled Jan 2023, registered May 2023).
  • Started Jan 2023; still recruiting 3 years 10 months later.

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Phase
Not applicable
Study type
Interventional
Enrollment
28
Allocation
Randomized
Ages
25 Years to 35 Years
Sex
Female
01

Where this study stands

Counted across the records on this site · 2026-11-13

Among 17 studies in Pre-Eclampsia with a site in Pakistan — 7 open to participants now, 7 under way, none of them phase 3. Pre-Eclampsia · Pakistan.

Planned enrollment
14th of 15
28 · median 146
Started
2023
the only one that year
No phase
10 of 17
4 open now
Registered
8th of 17
by date
Lead sponsor
2 of 17
Riphah International University

Among the 17 studies in Pre-Eclampsia with a site in Pakistan, this one is the 14th largest by planned enrollment of the 15 interventional ones that give a count, is the only one that started in 2023, is one of 10 with no phase, and was the 8th registered.

Pre-Eclampsia

916 studies on the registry are indexed under Pre-Eclampsia; 243 are open to participants now.

Browse Pre-Eclampsia studies →

Open to participants now

7 of the 17 studies in Pre-Eclampsia with a site in Pakistan are open now. Recruiting first, the newest first:

1 more — sign in →

All 7 open studies →

A study can be open while its sites in Pakistan have not opened yet or have stopped. Only those recruiting at a site in Pakistan →

Who these studies take

Of the 162 Pre-Eclampsia studies recruiting now, 81 (50%) set no upper age limit and 80 (49%) stop at 75 or younger; 18 take children under 18; 60 take healthy volunteers.

This study: 25 Years to 35 Years · female · no healthy volunteers.

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Watch this landscapeDownload CSVNarrow it in search →With an account: a weekly mail of what changed among 17 studies in Pre-Eclampsia with a site in Pakistan, or all of them as a file.
02

Study summary

To compare the effect of Jacobson's Relaxation Techniques and stretching exercises on Preeclampsia in pregnant women.

Read the detailed description

The effectiveness of Jacobson's progressive muscle relaxation technique on maternal, fetal, and neonatal outcomes in women with non-severe preeclampsiain have been studied in an RCT study. Pregnant women who use this technique experience reduced muscle tension and a sense of calm. in one of the study The Effect of Relaxation Techniques on Blood Pressure and Stress Among Pregnant Women with Mild Pregnancy Induced Hypertension were investigated in which Women with mild pregnancy-induced hypertension who used relaxation techniques saw significant improvements in their knowledge, physiological parameters, and blood pressure as well as a reduction in stress.

To the best of the researcher's knowledge, no comparative study has been done to yet to evaluate the efficacy of relaxation and stretching exercise. There is not enough data to determine whether Jacobson's relaxation techniques and stretching exercise reduce preeclampsia in pregnant women. As a result, this study will contribute to the expanding body of knowledge about which approach should be used as an alternative if results from other procedures are comparable

03

Conditions studied

  • Pre-Eclampsia; Complicating Pregnancy

Keywords

  • Pregnancy Toxemia,
  • Muscle Stretching Exercise
  • High Blood Pressure
04

Who can participate

Ages eligible
25 Years to 35 Years
Sexes eligible
Female
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Gestational age was exceeding 24 weeks
  • BP more than or up to 140/90
  • Diagnosed with gestational Hypertension
  • Primiparous

Exclusion criteria

Exclusion Criteria:

  • Women with history of preterm labor or repeated abortion
  • Bleeding
  • Intra uterine fetal growth anomalies
  • Underlying mental (depression with severe anxiety)
  • Cardio respiratory diseases
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Single (Participant)
Enrollment
28 participants (estimated)

Study arms

  • Experimental
    Stretching Exercises

    walking with stretching exercises

    Other: walking and Stretching

  • Active comparator
    Jacobson's Technique

    walking with Jacobson's Relaxation Technique.

    Other: walking and Jacobsons relaxation technique

Interventions

  • Otherwalking and Stretching

    Stretching exercise will be given for 6 weeks (3 sessions per week). 15 minutes of moderate walking with stretching exercises 5 times a week with Warm up and Cool down. Videos will be provided to participants to follow at home. Participants will be provided forms for home to fill after every session completed and frequency of each exercise

  • Otherwalking and Jacobsons relaxation technique

    Jacobson's Relaxation Technique will be given for 6 weeks. 15 minutes of moderate walking with Jacobson's Relaxation Technique. Videos will be provided to participants to follow at home. Participants will be provided forms for home to fill after every session completed. Participants will also bring their Pedometer

06

What researchers measure

Primary outcomes

  1. Mercury sphygmomanomete

    patient have systolic blood pressure of 140 mm Hg or higher and/or a diastolic blood pressure of 90 mm Hg or higher.

    Time frame: 4 Weeks

Secondary outcomes

  1. Pregnancy related anxiety questionnaire

    The degree of anxiety was estimated using Pregnancy related anxiety Questionnaire assessing the symptoms on scale 1 to 5 . 1 being not relevant and 5 relevant.

    Time frame: 4 Weeks

07

Study locations

1 of 1 sites recruiting
08

References and documents

Publications

  • Rana S, Lemoine E, Granger JP, Karumanchi SA. Preeclampsia: Pathophysiology, Challenges, and Perspectives. Circ Res. 2019 Mar 29;124(7):1094-1112. doi: 10.1161/CIRCRESAHA.118.313276. Erratum In: Circ Res. 2020 Jan 3;126(1):e8. doi: 10.1161/RES.0000000000000315. PubMed 30920918 ↗
  • Pacheco-Romero, J., Introduction to the Preeclampsia. Revista Peruana de Ginecología y Obstetricia, 2017. 63(2): p. 199-206.
  • Nirupama R, Divyashree S, Janhavi P, Muthukumar SP, Ravindra PV. Preeclampsia: Pathophysiology and management. J Gynecol Obstet Hum Reprod. 2021 Feb;50(2):101975. doi: 10.1016/j.jogoh.2020.101975. Epub 2020 Nov 7. PubMed 33171282 ↗
  • Awad MA, Hasanin ME, Taha MM, Gabr AA. Effect of stretching exercises versus autogenic training on preeclampsia. J Exerc Rehabil. 2019 Feb 25;15(1):109-113. doi: 10.12965/jer.1836524.262. eCollection 2019 Feb. PubMed 30899745 ↗
  • Ghorbannejad S, MehdizadehTourzani Z, Kabir K, MansourehYazdkhasti. The effectiveness of Jacobson's progressive muscle relaxation technique on maternal, fetal and neonatal outcomes in women with non-severe preeclampsia: a randomized clinical trial. Heliyon. 2022 Jun 13;8(6):e09709. doi: 10.1016/j.heliyon.2022.e09709. eCollection 2022 Jun. PubMed 35761936 ↗
  • Naseh, Z., P. Bahadoran, and M. Valiani, Effect of Relaxation Technique on Anxiety, Stress, and Depression Scores of High-risk Pregnant Women Prone to Preeclampsia and the Physiological Indicators of Their Babies. Avicenna Journal of Nursing and Midwifery Care, 2022. 30(3): p. 211-220.
  • Abd El Aliem, R.S., E.M. Abd-Elhakam, and S.A. Mustafa, Effect of Self Independence Physical Stretching Exercise on Feto-maternal Outcomes among Mild Preeclamptic Pregnant Women.
  • Vicente Bertagnolli T, Souza Rangel Machado M, Ferreira CJH, Machado JSR, Duarte G, Cavalli RC. Safety of a physical therapy protocol for women with preeclampsia: a randomized controlled feasibility trial. Hypertens Pregnancy. 2018 May;37(2):59-67. doi: 10.1080/10641955.2018.1439059. Epub 2018 Mar 1. PubMed 29495906 ↗
  • Caughey, M.C., et al., Abstract P035: Feasibility of Stretching Exercise for Prevention of Late-Onset Preeclampsia: A Pilot Trial. Circulation, 2018. 137(suppl_1): p. AP035-AP035.
  • Soliman, G.H., S.M.A. Elalem, and S.M. Elhomosy, The effect of relaxation techniques on blood pressure and stress among pregnant women with mild pregnancy induced hypertension. Asian Journal of Nursing Education and Research, 2017. 7(3): p. 321-329.

Individual participant data

Plan to share: No

09

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reachedSimilar studies: half by the dot; the band is the middle halfHalf of similar studies reached it by the dot; the band is the middle half, from a quarter to three quarters

Started Jan 2023 (actual). Primary completion is estimated for Jul 2023, 6 months after the start.

Of 171 non-industry interventional studies with no phase under Pre-Eclampsia, half reached primary completion within 24 months of starting (the median), counting those still running; a quarter within 9 and three quarters within 43. This study's planned 6 months is below that.

Counting every sponsor, half of 176 studies reached it within 24 months; a quarter within 9 and three quarters within 43.

How these figures are worked out, and which studies are left out of them.

Registered
May 9, 2023
First posted
May 18, 2023
StartActual
Jan 1, 2023
Primary completionEst.
Jul 1, 2023
CompletionEst.
Aug 1, 2023
Last update
May 18, 2023
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on May 18, 2023, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT05863962
Responsible party
Sponsor
First posted
May 18, 2023
Start date
Jan 1, 2023
Primary completion
Jul 1, 2023 (estimated)
Completion
Aug 1, 2023 (estimated)
Last update
May 18, 2023

Study contacts

Imran Amjad, PHD
Contact
imran.amjad@riphah.edu.pk
03324390125
Hafiza Mehjabeen
principal investigator · Riphah International University

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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