An observational study in Cirrhotic Patients With Spontaneous Bacterial Peritonitis, sponsored by Sohag University. Status unknown at 1 site in Egypt. Open to participants aged 15 Years to 100 Years. Per ClinicalTrials.gov, last updated 2023-05-09.
Sponsored by Sohag University · Observational
Spontaneous bacterial peritonitis (SBP) is a serious complication of ascites that can lead to death and can be described as an acute infection of ascites without any certain source of infection SBP is considered the most common infection in cirrhotic patients with ascites. SBP is diagnosed by the presence of ≥250 polymorphonuclear leukocyte (PMNL)/mm3 in the ascetic fluid in absence of surgical and treatable causes of intra-abdominal infections .
SBP has many pictures of clinical presentation SBP can be asymptomatic and patients pass unnoticed or can discovered accidentally may have local symptoms and signs of peritonitis such as abdominal pain, and tachypnea or may present with signs of deteriorated liver function in form of gastrointestinal bleeding, shock and renal failure An increasing amount of studies have demonstrated that peripheral blood neutrophil-to-lymphocyte ratio (NLR), monocyte-to-lymphocyte ratio (MLR), platelet-to-lymphocyte ratio (PLR) are indicators of systematic inflammatory response and are widely investigated as useful predictors of the clinical outcomes in various diseases .
185 studies on the registry are indexed under Peritonitis; 25 are open to participants now.
This study's planned enrollment of 300 is above the median of 127 across 59 observational studies indexed under Peritonitis.
Browse Peritonitis studies →Sohag University is the lead sponsor of 1,183 studies on the registry; 612 are open to participants now.
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Asses the value of blood platelets to lymphocytes ratio and monocytes to lymphocytes ratio as predictors of response for the treatment of spontaneous bacterial peritonitis in cirrhotic patients.
Exclusion Criteria:
Diagnostic Test: ascetic fluid study
ascetic fluid study parameter in diagnosis of spontaneous bacterial peritpnitis
Platelets to Lymphocytes Ratio and Monocytes to Lymphocytes Ratio as Predictors of Response to Treatment in Cirrhotic Patients with Spontaneous Bacterial Peritonitis
Spontaneous bacterial peritonitis (SBP) is a serious complication of ascites that can lead to death and can be described as an acute infection of ascites without any certain source of infection SBP is considered the most common infection in cirrhotic patients with ascites. SBP is diagnosed by the presence of ≥250 polymorphonuclear leukocyte (PMNL)/mm3 in the ascetic fluid in absence of surgical and treatable causes of intra-abdominal infections SBP has many pictures of clinical presentation SBP can be asymptomatic and patients pass unnoticed or can discovered accidentally may have local symptoms and signs of peritonitis such as abdominal pain, and tachypnea or may present with signs of deteriorated liver function in form of gastrointestinal bleeding, shock and renal failure
Time frame: 19/4/2023 - 30/4/2024
This study is status unknown, as verified in Apr 2023. You cannot join it, but the record below documents what was studied.
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Sohag University