An observational study in Neurological Complication, sponsored by Centre Hospitalier Universitaire de la Réunion. Recruiting at 1 site in Reunion. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-09-11.
Sponsored by Centre Hospitalier Universitaire de la Réunion · Observational
Non-invasive neuromonitoring tools such as transcranial doppler, optic nerve envelope diameter measurement and quantitative pupillometry are routinely used in acute brain injured patients as part of multimodal neuromonitoring with the aim, among others, of detecting episodes of intracranial hypertension, each method allowing the study of one of the different pathophysiological mechanisms of its impact.
However, at present there is no data in the literature on the value of these non-invasive neuromonitoring tools in the management of patients undergoing controlled intracranial surgery.
The study aims to help the early detection of postoperative neurological deterioration.
Patients undergoing planned neurosurgery
Exclusion Criteria:
4 days Post-operation follow-up. Data will be gathered before the surgery and at regular times after the surgery until day 4
Evolution of non-invasive neuromonitoring measures (using transcranial doppler)
This emasure will be performed bilaterally at the level of the first part of the middle cerebral artery, the values collected will be: * Systolic, mean and diastolic velocities; pulsatility index * Estimation of intracranial pressure
Time frame: From 1 hour before the surgery until Day 4 post-surgery
Evolution of non-invasive neuromonitoring measures (optic nerve envelope diameter)
The diameter of the optic nerve envelope will be collected bilaterally using an ultrasound machine
Time frame: From 1 hour before the surgery until Day 4 post-surgery
Evolution of non-invasive neuromonitoring measures (quantitative pupillometry)
The values collected will be : \- Size, quantification of the amplitude of variation to light, latency and speed of constriction of the pupil, presence or absence of anisocoria (defined by a difference \>1mm in size between the two pupils)
Time frame: From 1 hour before the surgery until Day 4 post-surgery
Plan to share: No
No publications or documents are linked to this record.
Eligibility is decided by the study team. Share this record with your doctor or contact the team directly.
Contact study teamGet an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
Centre Hospitalier Universitaire de la Réunion