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RecruitingNCT05812131COPEWebUpdated Aug 6, 2026

COPEWeb Training for Providers

An interventional study of COPEWeb online training and COPE In Person in PTSD and Substance Use Disorders, sponsored by VA Office of Research and Development. Recruiting at 1 site in United States. Open to participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-08-06.

Sponsored by VA Office of Research and Development · Not applicable, Interventional, and Health services research

From the registry’s dates

  • Started May 2025; still recruiting 1 year 4 months later.
Phase
Not applicable
Study type
Interventional
Enrollment
248
Allocation
Randomized
Ages
18 Years and older
Sex
All
01

Study summary

Post-traumatic stress disorder (PTSD) and substance use disorders (SUD) are two of the most common and debilitating mental health conditions afflicting military Veterans. PTSD and SUD frequently co-occur and are associated with poorer treatment outcomes. The investigators' team developed a trauma-focused intervention, Concurrent Treatment of PTSD and Substance Use Disorders Using Prolonged Exposure (COPE), which is identified by the VA as a gold standard of behavioral healthcare and was designated as a first-line treatment in the 2025 APA Clinical Practice Guideline for PTSD. However, a critical barrier to ensuring that Veterans with co-occurring PTSD/SUD receive evidence-based treatment is a lack of provider training. This project directly addresses this critical gap by developing a new web-based training program for providers (COPEWeb).

Read the detailed description

Background: PTSD is the most common mental health disorder among Veterans seeking treatment at Veterans Affairs (VA) hospitals, and more than half of Veterans with PTSD also meet criteria for a substance use disorder (SUD). To address the critical need for PTSD/SUD treatment, members of the investigative team developed Concurrent Treatment of PTSD and Substance Use Disorders Using Prolonged Exposure (COPE), an evidence-based, integrated, trauma-focused treatment identified by the VA as a gold standard of behavioral healthcare. Randomized controlled trials among Veterans demonstrate COPE's efficacy in significantly reducing PTSD and substance use. The majority of Veterans with PTSD/SUD prefer integrated treatment. Significance/Impact: At present, there is a critical shortage of clinicians trained to deliver COPE. Traditional in-person workshops are inefficient and costly. A poll of VA PTSD/SUD Specialists across the country found that 96.9% are interested in receiving COPE training and 99.1% would use a web-based training for COPE if available. A web-based resource for providers is ideal, as it can be rapidly disseminated, is easily accessible, and provides a significant amount of information in a standardized way. This project will directly address this critical gap in provider training to improve the care of Veterans with comorbid PTSD/SUD, enhance treatment delivery using innovative in-session provider assistance tools, and enhance knowledge of cost-benefit of technology-enhanced training. COPEWeb may be particularly useful for providers in rural clinic settings where mental health training is less accessible. This proposal has the potential for high military relevance and an immediate impact on dissemination and uptake of COPE, as well as a long-term impact on the overall health of the millions of Veterans suffering from co-occurring PTSD/SUD. Innovation: A new web-based provider training for COPE will be developed along with a highly innovative provider assistance toolkit to guide clinicians in real-time during sessions to enhance delivery and fidelity to the protocol and reduce provider burden. A panel of national VA experts and dissemination leaders will develop a best practice VA dissemination guideline on disseminating web-based provider trainings. The proposed project has the potential to significantly enhance provider training and increase patient access to evidence-based care. Furthermore, COPEWeb has the potential to serve a novel role in disaster planning to ensure mental health care providers are equipped to address the anticipated post-pandemic needs of Veterans given the rise in post-traumatic stress and alcohol/drug use during the pandemic. Specific Aims: This project aims to 1) develop a new web-based training protocol and innovative delivery aid system to strengthen providers' delivery of COPE to treat Veterans with PTSD/SUD with a high level of fidelity and competence, and 2) compare the COPEWeb training to in-person training on measures of knowledge, satisfaction, and behavior (i.e., fidelity). The cost effectiveness of web-based vs. in-person training will be examined. Methodology: The proposed methods and timeline for the development of COPEWeb are based on the team's prior success developing other widely-used provider training protocols (e.g., PEWeb, CBTIWeb). COPEWeb will be built and refined over the course of three strategic phases: content development, alpha-testing, and beta-testing. Following beta testing, the investigators will compare COPEWeb to in-person training among clinicians. Ongoing assessment will obtain qualitative and quantitative data on measures of provider satisfaction, knowledge, and behavior. Implementation/Next Steps: In collaboration with the investigators' operations partners, VA leadership, and EBP Coordinators, COPEWeb will be rapidly disseminated to mental health providers to increase adoption of evidence-based treatment for PTSD/SUD and improve the quality of mental health care for Veterans and the nation.

02

Conditions studied

  • PTSD
  • Substance Use Disorders

Keywords

  • PTSD
  • substance use disorders
  • training
  • providers
03

In context

Stress Disorders, Post-Traumatic

2,239 studies on the registry are indexed under Stress Disorders, Post-Traumatic; 554 are open to participants now.

This study's planned enrollment of 248 is above the median of 70 across 1,858 interventional studies indexed under Stress Disorders, Post-Traumatic.

Browse Stress Disorders, Post-Traumatic studies →

Lead sponsor

VA Office of Research and Development is the lead sponsor of 1,733 studies on the registry; 396 are open to participants now.

Of its 206 completed or terminated interventional studies of FDA-regulated products, 180 (87%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  • currently a provider in a behavioral health field (e.g., psychology, psychiatry, counseling)
  • English speaking
  • able to consistently obtain reliable internet access
  • willing to attend a 2-day "live" in-person (or virtual) COPE training if randomly assigned to that condition
  • willing to engage in a standardized patient assessment after training
  • has no prior formal training in the COPE therapy

Exclusion criteria

Exclusion Criteria:

  • received prior training in COPE
  • not a provider in the behavioral health field
  • non-English speaking
  • lack of reliable internet access
05

Study design

Phase
Not applicable
Primary purpose
Health services research
Allocation
Randomized
Intervention model
Factorial assignment
Masking
None (open label)
Enrollment
248 participants (estimated)

Study arms

  • Experimental
    COPEWEb

    online COPEWeb training

    Behavioral: COPEWeb online training

  • Active comparator
    COPE In person

    COPE training delivered in person

    Behavioral: COPE In Person

Interventions

  • BehavioralCOPEWeb online training

    COPE training delivered via online COPEWEb to providers

  • BehavioralCOPE In Person

    COPE training provided in person to providers

06

What researchers measure

Primary outcomes

  1. IBM Computer Usability Satisfaction Questionnaires (CSUQ)

    The CSUQ is a 19-item Likert-type (7-point \[strongly agree to strongly disagree\]) questionnaire that provides an overall usability satisfaction score along with subscales that measure program usefulness, information quality, and interface quality. The CSUQ measure and subscales have good reliability, sensitivity, and validity.

    Time frame: Through study completion, an average of 8 weeks

  2. COPE Knowledge Acquisition Test (CKAT)

    The CKAT will be completed at pre- and post-training. The 20-item measure will be scored and the percent of items answered correctly (rated from 0 to 100% correct) will be assessed. Higher scores represent greater knowledge.

    Time frame: Change from baseline to study completion, an average of 8 weeks

07

Study locations

1 of 1 sites recruiting
  • Ralph H. Johnson VA Medical Center, Charleston, SC
    Charleston, South Carolina 29401-5703, United States
    • Sudie E Back, PhD · Contact · Sudie.Back@va.gov · (843) 792-9383
    • Sudie E. Back, PhD · Principal investigator
    Recruiting
08

References and documents

Publications

  • Gujral K, Scott JY, Dismuke-Greer CE, Jiang H, Illarmo S, Wong E, Chow A, Yoon J. Impact of VA's Clinical Resource Hub Primary Care Telehealth Program on Health Care Use and Costs. Med Care. 2025 Dec 1;63(12):888-898. doi: 10.1097/MLR.0000000000002206. Epub 2025 Sep 22. PubMed 40981648 ↗

Individual participant data

Plan to share: No

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Aug 6, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT05812131
Lead sponsor
VA Office of Research and Development
Collaborators
Medical University of South Carolina, National Center for PTSD
Responsible party
Sponsor
First posted
Apr 13, 2023
Start date
May 11, 2025
Primary completion
Jan 1, 2027 (estimated)
Completion
Apr 5, 2027 (estimated)
Last update
Aug 6, 2026

Study contacts

Sudie E Back, PhD
Contact
Sudie.Back@va.gov
(843) 792-9383
Stacey S Sellers, MS
Contact
Stacey.Sellers@va.gov
(843) 789-6703 ext. 206703
Sudie E. Back, PhD
principal investigator · Ralph H. Johnson VA Medical Center, Charleston, SC

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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