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CompletedNCT05798975Updated May 14, 2025

Analysis of Heart Rate Variability After a Physical Exercise Session

An interventional study of Aerobic Exercise. 1 session of acute exercise and Resistance Exercise. 1 session of acute exercise in Hypertension, sponsored by Instituto de Cardiologia do Rio Grande do Sul. Completed at 1 site in Brazil. Open to participants aged 30 Years to 59 Years. Per ClinicalTrials.gov, last updated 2025-05-14.

Sponsored by Instituto de Cardiologia do Rio Grande do Sul · Not applicable, Interventional, and Health services research

From the registry’s dates

  • Registered 10 months after the study started (first participant enrolled Apr 2022, registered Feb 2023).
Phase
Not applicable
Study type
Interventional
Enrollment
36
Allocation
Randomized
Ages
30 Years to 59 Years
Sex
All
01

Study summary

Systemic arterial hypertension (SAH) is a multifactorial clinical condition, characterized by sustained elevation of blood pressure levels, contributing to 50% of deaths from cardiovascular disease. The Autonomic Nervous System (ANS) plays a fundamental role in the regulation of Blood Pressure (BP) and is closely associated with Heart Rate (HR). HR changes are called Heart Rate Variability (HRV). In individuals with SAH, HRV indices are reduced compared to normotensive individuals, showing changes in autonomic modulation, thus increasing the risk for cardiovascular events. The objective of this study will be to analyze the Heart Rate Variability in individuals with controlled SAH after a session of aerobic (EA) or resistance (RE) physical exercise.

Read the detailed description

Controlled hypertensive individuals aged between 30 and 59 years will be selected, for convenience, who use the services of the Instituto de Cardiologia do Rio Grande do Sul. Volunteers will be randomly assigned to an EA session (40 minutes on cycle ergometer, 60% of heart rate reserve) or RE (2 exercises for lower limbs and 2 for upper limbs with 4 sets of 12 repetitions at 60% 1-RM) or control group without exercise. HRV data will be collected by ECG (Wincardio USB - Version 11.1.0.0, MICROMED Biotecnologia Ltda, Brasília - DF - Brazil) during 10 minutes before the exercise session, 10 minutes after the exercise session, 1h and 2h post-session . It is expected to estimate results that may demonstrate clarifications about the impact of a physical exercise session on HRV in controlled hypertensive individuals.

02

Conditions studied

  • Hypertension

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03

In context

Hypertension

6,689 studies on the registry are indexed under Hypertension; 965 are open to participants now.

This study's enrollment of 36 is below the median of 90 across 4,995 interventional studies indexed under Hypertension.

Browse Hypertension studies →

Lead sponsor

Instituto de Cardiologia do Rio Grande do Sul is the lead sponsor of 74 studies on the registry; 10 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
30 Years to 59 Years
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • Controlled Systemic Alterial Hypertension

Exclusion criteria

Exclusion Criteria:

  • Diabetes mellitus;
  • heart failure;
  • coronary artery disease;
  • chronic renal failure;
  • body mass index (BMI) ≥ 35 kg/m2;
  • smokers;
  • individuals with injuries to the upper and lower limbs that make the exercise protocol impossible;
  • not using antihypertensive medication and using beta-blocker and/or alpha-blocker medication.
05

Study design

Phase
Not applicable
Primary purpose
Health services research
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Double (Participant, Care provider)
Enrollment
36 participants (actual)

Study arms

  • Experimental
    Aerobic Physical Exercise

    Cycle ergometer exercise

    Other: Resistance Exercise. 1 session of acute exercise · Other: no exercise

  • Experimental
    Resistance Physical Exercise

    Exercise with weights

    Other: Aerobic Exercise. 1 session of acute exercise · Other: no exercise

  • No intervention
    Control

    No exercise. Rest

Interventions

  • OtherAerobic Exercise. 1 session of acute exercise

    40 minutes on cycle ergometer, 60% of heart rate reserve

  • OtherResistance Exercise. 1 session of acute exercise

    2 exercises for lower limbs and 2 for upper limbs with 4 sets of 12 repetitions at 60% 1-RM. 40 minutes

  • Otherno exercise

    Rest

06

What researchers measure

Primary outcomes

  1. Heart Rate Variability.

    Analysis of heart rate variability with Wincardio Digital ECG.

    Time frame: 4 hours

07

Study locations

1 site
  • Diego Silveira da Silva
    Porto Alegre, RS, Brazil
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on May 14, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT05798975
Lead sponsor
Instituto de Cardiologia do Rio Grande do Sul
Responsible party
Diego Silveira da Silva (physical education professor., Instituto de Cardiologia do Rio Grande do Sul) — Principal investigator
First posted
Apr 5, 2023
Start date
Apr 1, 2022
Primary completion
Oct 1, 2024
Completion
Nov 30, 2024
Last update
May 14, 2025

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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This study is completed, as verified in May 2025. You cannot join it, but the record below documents what was studied.

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