An interventional study of Video 360 and Standard videos in Anomic Aphasia, sponsored by Catholic University of the Sacred Heart. Suspended at 1 site in Italy. Open to participants aged 18 Years to 80 Years. Per ClinicalTrials.gov, last updated 2026-03-19.
Sponsored by Catholic University of the Sacred Heart · Not applicable, Interventional, and Treatment
Aphasia is an acquired deficit following acute damage to the central nervous system that involves the difficulty or impossibility of understanding and formulating language. A typical disorder of non-fluent forms of aphasia is anomia. Anomia refers to the difficulty in finding words, in particular when trying to name objects and actions. According to the Embodied Cognition approach (EC), language is tightly connected to the motor system. In this view, language rehabilitation programs should stimulate language through the activation of the motor system. In this approach, since anomic deficits are often due to a weak link between the meaning of the word and its lemma, the Hebbs' principles of coincident and correlated learning can be exploited, i.e., by intensifying the synchronous activation of lexicon and semantics and connecting them with the motor counterpart. In this study, the investigators present an innovative training, based on the EC framework, in which they will make use of new technologies for anomia rehabilitation in post-stroke patients. Specifically, the researchers will use immersive 360° videos representing everyday actions displayed from the first-person point of view, experienced through a head-mounted display. The training will be administered 3 times a week for 4 weeks. The control group will watch standard videos representing the same actions recorded from the third-person perspective. Naming abilities will be tested before and after the training together with other cognitive and psychological measures. The investigators expect that the group who will undergo the 360° video-based training will show greater improvement of performance compared to the control group.
47 studies on the registry are indexed under Anomia; 9 are open to participants now.
This study's planned enrollment of 40 is above the median of 24 across 43 interventional studies indexed under Anomia.
Browse Anomia studies →Catholic University of the Sacred Heart is the lead sponsor of 237 studies on the registry; 29 are open to participants now.
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Exclusion Criteria:
Patients will watch spherical videos displaying everyday actions towards objects; an audio is embedded describing the action and the object represented (i.e. "I'm cutting the potatoes").
Behavioral: Video 360
Patients will watch standard videos displaying everyday actions towards objects; an audio is embedded describing the action and the object represented (i.e. "I'm cutting the potatoes")
Behavioral: Standard videos
Patients will undergo 12 sessions, 3 per weeks, 4 weeks
Patients will undergo 12 sessions, 3 per weeks, 4 weeks
Number of verbs and objects correctly named
All the trained videos will be presented and the patient will be asked to name the verb and the object depicted. The accuracy will be registered
Time frame: post treatment, 1 month
Batteria per l'Analisi dei Deficit Afasici (BADA), naming subtest
It is an Italian validated neuropsychological battery aiming at testing all the language abilities. It includes several tests tapping into the different linguistic abilities, but for the purpose of the present study only the verb and object naming subtest will be administered. Higher scores indicate greater naming abilities
Time frame: post treatment, 1 month
EuroQol Health-related quality of life (EQ-5D-3L)
The test consists of 2 sections. The first one is made of 5 questions scored from 1 to 5 points each. The final score ranges from 5 to 15, where the lesser the better. The second section is a visual scale on which the best state the patient can imagine is marked 100 and the worst state is marked 0.
Time frame: post treatment, 1 month
Functional Outcome Questionnaire (FOQ-A)
The survey is administered to the caregiver. It includes 32 questions each scored from 1 to 5 points. The final scores ranges from 32 to 160, where higher scores indicate greater communication abilities
Time frame: post treatment, 1 month
Ran from May 2023 to primary completion in Dec 2025, 31 months.
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This study is suspended, as verified in Sep 2025. You cannot join it, but the record below documents what was studied.
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