An observational study in Pain, sponsored by Hasselt University. Completed at 4 sites in 2 countries. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2024-07-12.
Sponsored by Hasselt University · Observational
This project aims to provide values of test-retest reliability and insights from concurrent validity of outcome measures for pain in multiple sclerosis.
Pain is one of the most annoying symptoms in multiple sclerosis (MS). However, it is underestimated albeit its high prevalence rate with 63%. It negatively affects health related quality of life, activity of daily living, mental health, social functioning, employment, sleep and life enjoyment. In literature, the prevalence of pain varies in the MS literature from 29% to 86%. This wide-range prevalence is the result of methodological differences and non-uniformity of the studied populations which makes pain unclear and underdiagnosed in multiple sclerosis.It is hypothesized that the consistency, severity and interference of pain have varying relationships between other factors such as depression, anxiety, sleep or fatigue.
Evaluating pain was done with various outcome measures resulting in inconclusive results. However, very few of the pain outcome measures are validated for MS population. Thus, it cannot be advised yet whether they contain similar or complementary information. Finally, the interference of pain on activities and participation level of the International Classification of Functioning, Disability and Health (ICF) is poorly documented.
This project aims to put the foundations for future interventional research by providing values of test-retest reliability and insights from concurrent validity. As well, the perceived interference from pain on activities and participation level will be documented.
2,450 studies on the registry are indexed under Pain; 945 are open to participants now.
This study's enrollment of 60 is below the median of 100 across 301 observational studies indexed under Pain.
Browse Pain studies →Hasselt University is the lead sponsor of 203 studies on the registry; 31 are open to participants now.
Counted across the registry records on this site, refreshed daily.
People with MS with pain
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Douleur Neuropathique 4 (DN4) Questionnaire
screening tool
Time frame: Day 1 and day 7
PainDETECT Questionnaire
screening tool
Time frame: Day 1 and day 7
Ran from Apr 2023 to primary completion in Apr 2024, 12 months.
Of 147 non-industry observational studies under Pain, half reached primary completion within 25 months of starting (the median), counting those still running; a quarter within 11 and three quarters within 71. This study's 12 months is below that.
Counting every sponsor, half of 154 studies reached it within 23 months; a quarter within 11 and three quarters within 71.
How these figures are worked out, and which studies are left out of them.
This study is completed, as verified in Jul 2024. You cannot join it, but the record below documents what was studied.
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