CClinicalTrials.gg
CompletedNCT05725122Updated Feb 13, 2023

Stone Clearance in Patients With Upper Ureteric Stones Using Extracorporeal Shock Wave Lithotripsy Compared With Extracorporeal Shock Wave Lithotripsy Combined With Tamsulosin Therapy

An interventional study of Extracorporeal shock wave lithotripsy and Extracorporeal Shock Wave Lithotripsy combined with Tamsulosin Therapy. in Renal Stone, sponsored by Services Hospital, Lahore. Completed at 1 site in Pakistan. Open to participants aged 18 Years to 70 Years. Per ClinicalTrials.gov, last updated 2023-02-13.

Sponsored by Services Hospital, Lahore · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Registered 5 years after the study started (first participant enrolled Feb 2018, registered Feb 2023).
Phase
Not applicable
Study type
Interventional
Enrollment
82
Allocation
Randomized
Ages
18 Years to 70 Years
Sex
All
01

Study summary

Extracorporeal shock wave lithotripsy (ESWL) is the least invasive and effective treatment for upper ureteric stones with a stone clearance rate of 60-90%. Tamsulosin is an alpha-blocker widely used in urological practice to relax smooth muscle of the prostate and bladder neck. Its role as part of medical expulsion therapy for the treatment of patients with kidney and ureteric stones has proved to be of considerable success. However, its role in clearing upper ureteric stones as an adjunct to ESWL is controversial. Therefore, this study will be conducted to evaluate its role in stone clearance along with extracorporeal shock wave lithotripsy in patients with upper ureteric stones

02

Conditions studied

03

In context

Kidney Calculi

598 studies on the registry are indexed under Kidney Calculi; 163 are open to participants now.

This study's enrollment of 82 is close to the median of 90 across 461 interventional studies indexed under Kidney Calculi.

Browse Kidney Calculi studies →

Lead sponsor

Services Hospital, Lahore is the lead sponsor of 33 studies on the registry; 1 is open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 70 Years
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • single upper ureteric stone
  • size ranging from 6-15 mm
  • stones history less than 6 months

Exclusion criteria

Exclusion Criteria:

  • Patients with urinary tract infection
  • multiple ureteric stones,
  • presence of a ureteric stricture distal to the stone,
  • previous unsuccessful ESWL,
  • concomitant use of calcium channel blockers or alpha-adrenergic antagonists
  • patients with abnormal coagulation profile
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Single (Participant)
Enrollment
82 participants (actual)

Study arms

  • Active comparator
    ESWL alone

    Extracorporeal shock wave lithotripsy will be given to the patient

    Procedure: Extracorporeal shock wave lithotripsy

  • Active comparator
    ESWL combined with tamsulosin therapy

    Extracorporeal shock wave lithotripsy combined with tamsulosin therapy will be given to the patient

    Procedure: Extracorporeal Shock Wave Lithotripsy combined with Tamsulosin Therapy.

Interventions

  • ProcedureExtracorporeal shock wave lithotripsy

    Extracorporeal shock wave lithotripsy will given to the patients

  • ProcedureExtracorporeal Shock Wave Lithotripsy combined with Tamsulosin Therapy.

    Extracorporeal Shock Wave Lithotripsy combined with Tamsulosin Therapy will be given to the patients

06

What researchers measure

Primary outcomes

  1. stone clearance

    Number of patients cleared from ureteric stones

    Time frame: 4 weeks

07

Study locations

1 site
  • services Institute of Medical Sciences
    Lahore, Punjab, Pakistan
08

References and documents

Individual participant data

Plan to share: Undecided

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Feb 13, 2023, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT05725122
Lead sponsor
Services Hospital, Lahore
Responsible party
Dr. SamiUllah (Principal Investigator, Services Hospital, Lahore) — Principal investigator
First posted
Feb 13, 2023
Start date
Feb 1, 2018
Primary completion
Dec 31, 2021
Completion
Dec 31, 2021
Last update
Feb 13, 2023

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Feb 2023. You cannot join it, but the record below documents what was studied.

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Sign in to follow

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Start the discussion