An interventional study of Contrast dose reduction, CT-angiography in Aortic Aneurysm, sponsored by Universitaire Ziekenhuizen KU Leuven. Completed. Open to participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2023-02-08.
Sponsored by Universitaire Ziekenhuizen KU Leuven · Not applicable, Interventional, and Diagnostic
An in-house calculator was developed to calculate the appropriate contrast dose, rather than standardly administering a 120ml dose. This study aims for a more uniform contrast enhancement in patients by means of adjusting (lowering) contrast dose to patient parameters.
Until now, CT scans in our and many other institutions are being performed with a fixed standard contrast dose specific for every protocol, independent of patient characteristics. However, many if not all patients would benefit from a contrast dose reduction, as long as image quality is not impaired. This is especially beneficial to patients with impaired renal function.
For this purpose, we researched previous literature as well as data from previously scanned patients with standard dose, to formulate a contrast dose calculation adapted to patient parameters.
An in-house calculator was developed to calculate the optimal contrast dose dependent on patient length, weight and heartrate.
A total of 60 CT-scans will be performed and retrospectively collected. Patients are randomly assigned to one of three groups : 1/ Standard dose of 120ml; 2/ Calculated dose (40-150ml) 3/ Calculated dose -50% (20-120ml). In case of reduced kidney function, patients were randomly divided between group 2 and 3 (reduced contrast dose).
960 studies on the registry are indexed under Aneurysm; 175 are open to participants now.
This study's enrollment of 60 is below the median of 72 across 462 interventional studies indexed under Aneurysm.
Browse Aneurysm studies →Universitaire Ziekenhuizen KU Leuven is the lead sponsor of 928 studies on the registry; 261 are open to participants now.
Of its 5 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Standard contrast dose administration
Other: Contrast dose reduction, CT-angiography
Contrast dose by calculation
Other: Contrast dose reduction, CT-angiography
Contrast dose by calculation, with extra dilution by 50%.
Other: Contrast dose reduction, CT-angiography
Contrast dose reduction for CT-angiography in pre-operative aorta
Reduction in contrast dose
Reduction in contrast dose while maintaining image quality
Time frame: Through study completion, an average of 1 year
No study locations are listed for this record.
This study is completed, as verified in Dec 2015. You cannot join it, but the record below documents what was studied.
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Universitaire Ziekenhuizen KU Leuven