An observational study in COVID-19, sponsored by Universidade Federal do Rio de Janeiro. Completed at 3 sites in Brazil. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2024-01-30.
Sponsored by Universidade Federal do Rio de Janeiro · Observational
This observational and retrospective study will follow the recommendations of the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE). The aim is to verify and analyze the clinical and laboratory variables with prediction capability for indication of invasive ventilatory support in patients with COVID-19. The present study will be carried out in specific care units for patients with suspected or confirmed COVID-19. Individuals with suspected or clinical diagnosis of COVID-19, with a minimum hospital stay of 24 hours and submitted to oxygen therapy or non-invasive ventilation will be selected. Clinical and laboratory variables will be collected from the moment of admission and every 12 hours until the third day of hospitalization. The primary outcome will be rate of endotracheal intubation, while secondary outocomes will be lenght of stay in intensive care unit, and hospital, as well as mortality rate.
Clinical and laboratory data will be collected from medical records from the period of the COVID-19 pandemic (February 2020 to June 2021)
7,640 studies on the registry are indexed under COVID-19; 488 are open to participants now.
This study's enrollment of 350 is above the median of 261 across 3,136 observational studies indexed under COVID-19.
Browse COVID-19 studies →Universidade Federal do Rio de Janeiro is the lead sponsor of 120 studies on the registry; 11 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Patients with confirmation of covid-19 and with length of stay in the intensive care unit greater than 48 hours will be selected for the intubated and non-intubated groups. For the intubated group, patients who underwent endotracheal intubation after 48 hours of admission to the intensive care unit will be selected. For the non-intubated group, those patients who were not intubated during their stay in the intensive care unit will be selected.
Exclusion Criteria:
Composed of Patients who were intubated after 48 hours of admission to the intensive care unit
Procedure: orotracheal intubation
Composed of patients who were not intubated during their stay in the intensive care unit
Clinical and laboratory data will be collected from patients who are intubated after 48 hours of admission to the intensive care unit
Also known as: invasive mechanical ventilation
Identify clinical and laboratory variables that may be associated with the need of endotracheal intubation in the first 72 hours of admission to the intensive care unit.
Vital signs will be collected through the cardiac monitor and clinical evaluation from the moment of admission until the third day of hospitalization, every twelve hours and full blood count and biochemistry data will be collected from patients at admission until the third day of hospitalization in the intensive care unit
Time frame: 3 days
time to endotracheal intubation
It will be collected from the date of intensive care unit admission until the date of endotracheal intubation
Time frame: 28 days
length of stay in the ICU
It will be collected from the date of intensive care unit admission until the outcome of discharge from the intensive care unit or death.
Time frame: 6 months
length of hospital
It will be collected from the date of intensive care unit admission until the outcome of hospital discharge or death.
Time frame: 12 months
mechanical ventilation days
It will be collected from the date of intubation in the intensive care unit until the date of extubation or up to 48 hours off mechanical ventilation in cases of tracheostomized patients and/or until the outcome of death
Time frame: 6 months
hospital mortality
Mortality will be collected during the period of hospitalization
Time frame: 12 months
This study is completed, as verified in Jan 2024. You cannot join it, but the record below documents what was studied.
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Universidade Federal do Rio de Janeiro