An interventional study of Kono-S group and Side-to-side group in Crohn Disease and Recurrence, sponsored by Jinling Hospital, China. Recruiting at 1 site in China. Open to participants aged 16 Years to 60 Years. Per ClinicalTrials.gov, last updated 2022-12-20.
Sponsored by Jinling Hospital, China · Not applicable, Interventional, and Treatment
The postoperative recurrence of Crohn's diseases (CD) remains high. Stapled anti-mesenteric functional end-to-end anastomosis was safe for CD patients. Its impact on the postoperative recurrence of CD was unknown. Whether it is superior than the conventional anastomosis (stapled antimesenteric isoperistaltic side-to-side anastomosis) needs explored. The trial aims to compare the different impacts of the two antimesenteric anastomosis configurations on the anastomotic recurrence following bowel resection.
1,880 studies on the registry are indexed under Crohn Disease; 462 are open to participants now.
This study's planned enrollment of 236 is above the median of 66 across 1,188 interventional studies indexed under Crohn Disease.
Browse Crohn Disease studies →Jinling Hospital, China is the lead sponsor of 126 studies on the registry; 34 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
patients in this arm will receive stapled Kono-S anastomosis after bowel resection
Procedure: Kono-S group
patients in this arm will receive stapled antimesenteric isoperistaltic side-to-side anastomosis after bowel resection
Procedure: Side-to-side group
patients in this arm will receive stapled Kono-S anastomosis after bowel resection
patients in this arm will receive stapled antimesenteric isoperistaltic side-to-side anastomosis after bowel resection
the endoscopic recurrence rate at 1 year after surgery
the endoscopic recurrence rate at 1 year after surgery
Time frame: at 1 year after surgery(6-18month)
the clinical recurrence rate at 1 and 5 year after surgery
the clinical recurrence rate at 1 and 5 year after surgery
Time frame: 1 and 5 year after surgery
the surgical recurrence rate at 1 and 5 year after surgery
the surgical recurrence rate at 1 and 5 year after surgery
Time frame: 1 and 5 year after surgery
the endoscopic recurrence rate at 1 year after surgery
the endoscopic recurrence rate at 1 year after surgery
Time frame: 1 and 5 year after surgery
quality of life for CD patients inflammatory bowel disease questionnaire(IBDQ)
IBDQ ， higher means better，IBDQ，7-224；
Time frame: 1 and 5 year after surgery
quality of life for CD patients Short Form 12
Short Form 12 ， higher means better，Short Form-12， 0-12；
Time frame: 1 and 5 year after surgery
Plan to share: No
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Jinling Hospital, China