An observational study in Zonule of Zinn Abnormality and Zonular Cataract, sponsored by Wenzhou Medical University. Status unknown at 1 site in China. Per ClinicalTrials.gov, last updated 2022-12-20.
Sponsored by Wenzhou Medical University · Observational
The purpose of this study is to evaluate the intra-examiner repeatability and inter-examiner reproducibility in lens zonule length measurements using very high-frequency (VHF) digital ultrasound (ArcScan Insight 100).
1,701 studies on the registry are indexed under Cataract; 230 are open to participants now.
This study's planned enrollment of 45 is below the median of 81 across 484 observational studies indexed under Cataract.
Browse Cataract studies →Wenzhou Medical University is the lead sponsor of 93 studies on the registry; 8 are open to participants now.
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Healthy subjects with no ocular disease except ametropia
Exclusion Criteria:
Device: ArcScan Insight 100 very high-frequency digital ultrasound
The Insight-100 (ArcScan Inc., Golden, CO, USA) employs the high-frequency B-scan in the assessment of anterior segment parameters. Anormal saline coupling medium is formed with a disposable eyepiece between the 50 MHz transducer and the eye. The instrument moves the transducer in an arc so that the beam axis maintains approximate normality to the surface of the eye. The frequencies of cornea, anterior chamber, and lens are 60 MHz, 50 MHz and 50 MHz, respectively. The maximum arc scanning range is 70 degrees, and there is a linear scanning range of 29mm. The axial and lateral resolutions are 35 μm and 65 μm, respectively. It can measure structures behind the iris, including lens zonule.
Repeatability of ArcScan Insight 100 zonule scans in normal eyes (standard deviation and coefficient of variation)
First, three images will be obtained under'capsule model'using ArcScan Insight 100, and the length of zonule will be measured with built-in software by operator A. Operator B then performed the measurements using the same procedure and technique. The standard deviation and coefficient of variation of 3 repeated measurements for zonule length. will be calculated.
Time frame: 1 day
Reproducibility of ArcScan Insight 100 zonule scans in normal eyes
First, three images will be obtained under'capsule model'using ArcScan Insight 100, and the length of zonule will be measured with built-in software by operator A. Operator B then performed the measurements using the same procedure and technique. The intraclass correlation is used to evaluate the difference between operator A and operator B.
Time frame: 1 day
Repeatability of zonule length measurement with the built-in software (the intraclass correlation)
After a 1-month period, operator A and operator B will measure the zonule length again. The intraclass correlation is used to evaluate the difference between the two repeated measurements of one same image by Operator A or Operator B.
Time frame: 1 month
Plan to share: No
This study is status unknown, as verified in Dec 2022. You cannot join it, but the record below documents what was studied.
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Wenzhou Medical University