An observational study in Colorectal Cancer and Colorectal Neoplasms, sponsored by Fudan University. Status unknown at 1 site in China. Open to participants aged 50 Years to 75 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2022-12-06.
Sponsored by Fudan University · Observational
The incidence rate and mortality of colorectal cancer are increasing year by year. Most colorectal cancer develops from colorectal adenoma and is a disease that can be prevented and controlled. Thanks to early screening, the incidence rate and mortality of colorectal cancer have declined year by year. However, due to poor compliance with colonoscopy and the lack of efficient and convenient early screening methods, it is difficult to screen for colorectal cancer in China. According to the data from Shanghai Xuhui District Center for Disease Control and Prevention, the proportion of colonoscopies in high-risk groups for colorectal cancer is less than 18%.
This project plans to use the latest colorectal cancer screening technology, namely, 5hmC detection in peripheral blood and DNA methylation detection in feces, for those who are positive in the colorectal cancer incidence risk questionnaire or fecal occult blood in Xuhui District, Shanghai. It is strongly recommended that subjects with positive screening should undergo colonoscopy, to effectively improve the rate of colonoscopy and the early diagnosis rate of colorectal cancer. At the same time, to explore the screening efficiency of the early diagnosis model of 5hmC cancer.
5,738 studies on the registry are indexed under Colorectal Neoplasms; 1,481 are open to participants now.
This study's planned enrollment of 10,000 is above the median of 250 across 1,253 observational studies indexed under Colorectal Neoplasms.
Browse Colorectal Neoplasms studies →Fudan University is the lead sponsor of 1,308 studies on the registry; 637 are open to participants now.
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Residents of Xuhui District, Shanghai, who are initially screened as high-risk for colorectal cancer by Shanghai Xuhui District Center for Disease Control and Prevention, and do not receive a colonoscopy. People who are willing to accept the screening program.
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Age ≥ 50 years old and\<75 years old;
Exclusion Criteria:
① History of colorectal cancer, colorectal adenoma, and treatment;
Proportion of subjects receiving colonoscopy
Proportion of subjects receiving colonoscopy
Time frame: Three years
Proportion of subjects suffering early colorectal cancer
Proportion of stageⅠcancer in total colorectal cancer
Time frame: Three years
Sensitivity and specificity of the model in the diagnosis of colorectal cancer and adenoma
Sensitivity and specificity of the model in the diagnosis of colorectal cancer and adenoma
Time frame: Three years
This study is status unknown, as verified in Nov 2022. You cannot join it, but the record below documents what was studied.
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