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RecruitingNCT05634135Updated Dec 30, 2024

Lung Ventilation and Perfusion in Different Phenotypes of Chronic Critical Illness With Prolonged Mechanical Ventilation

An observational study in Prolonged Mechanical Ventilation, sponsored by National Taiwan University Hospital. Recruiting at 1 site in Taiwan. Open to participants aged 20 Years and older. Per ClinicalTrials.gov, last updated 2024-12-30.

Sponsored by National Taiwan University Hospital · Observational

From the registry’s dates

  • Primary completion was expected by Feb 2025, 1 year 7 months ago, but the record still lists the study as recruiting.
  • Started Jul 2022; still recruiting 4 years 2 months later.
Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
103
Ages
20 Years and older
Sex
All
01

Study summary

This project will conduct a series of analysis of physiological and clinical data on tracheostomy patients who receive prolonged mechanical ventilation, hoping to find out the different manifestations of patients through the investigation by a variety of physiologic measurements, so as to understand whether different types of patients phenotype to derive different clinical strategies for liberation of the mechanical ventilator.

02

Conditions studied

  • Prolonged Mechanical Ventilation

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Keywords

  • Ventilation
  • mechanical ventilation
  • weaning
  • oxygen uptake
03

In context

Critical Illness

1,881 studies on the registry are indexed under Critical Illness; 462 are open to participants now.

This study's planned enrollment of 103 is below the median of 130 across 867 observational studies indexed under Critical Illness.

Browse Critical Illness studies →

Lead sponsor

National Taiwan University Hospital is the lead sponsor of 2,563 studies on the registry; 569 are open to participants now.

Of its 11 completed or terminated interventional studies of FDA-regulated products, 2 (18%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
20 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Chronic critically ill patients receiving prolonged mechanical ventilation

Inclusion criteria

  • Patients with at least 10 days of mechanical ventilation at the intensive care unit of National Taiwan University Hospital and transferred to the Respiratory Care Center of National Taiwan University Hospital for weaning training
  • Patients who have undergone tracheostomy and still have a tracheotomy tube
  • Are at least 20 years old
  • Stable respiratory condition with inspired oxygen fraction not exceeding 50%

Exclusion criteria

Exclusion Criteria:

  • Hemodynamic instability or continuous use of vasopressors
  • Pregnancy
05

Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
103 participants (estimated)
Patient registry
No
06

What researchers measure

Primary outcomes

  1. Liberation from mechanical ventilation at discharge from the weaning unit

    At least five consecutive days of free from mechanical ventilation ventilation

    Time frame: Five days

07

Study locations

1 of 1 sites recruiting
  • National Taiwan University Hospital
    Taipei City, Taiwan
    Recruiting
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Dec 30, 2024, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT05634135
Lead sponsor
National Taiwan University Hospital
Responsible party
Sponsor
First posted
Dec 1, 2022
Start date
Jul 31, 2022
Primary completion
Feb 17, 2025 (estimated)
Completion
Feb 17, 2025 (estimated)
Last update
Dec 30, 2024

Study contacts

Jih-Shuin Jerng, MD, PhD
Contact
jsjerng@ntu.edu.tw
+886-2-23123456 ext. 263532
Jih-Shuin Jerng, MD, PhD
principal investigator · National Taiwan University Hospital

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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