ClinicalTrials.gg
Status unknownNCT05603221Updated Nov 2, 2022

Renal Perfusion Assessment in the Endovascular Treatment of Renal Artery Stenosis

An observational study in Renal Artery Stenosis, sponsored by Peking Union Medical College Hospital. Status unknown at 1 site in China. Open to participants aged 18 Years to 80 Years. Per ClinicalTrials.gov, last updated 2022-11-02.

Sponsored by Peking Union Medical College Hospital · Observational

The sponsor has not verified this record recently (last verified Oct 2022), so the status shown — last known as Recruiting — may be out of date.
Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
30
Ages
18 Years to 80 Years
Sex
All
01

Study summary

The clinical benefits of endovascular treatment in renal artery stenosis remain controversial. This study uses arterial spin labelling MRI and flat-panel detector parenchymal blood volume imaging to observe the change in renal perfusion after endovascular treatment in renal artery stenosis.

02

Conditions studied

  • Renal Artery Stenosis

Keywords

  • renal artery stenosis
  • renal perfusion
03

In context

Renal Artery Obstruction

58 studies on the registry are indexed under Renal Artery Obstruction; 8 are open to participants now.

This study's planned enrollment of 30 is below the median of 80 across 15 observational studies indexed under Renal Artery Obstruction.

Browse Renal Artery Obstruction studies →

Lead sponsor

Peking Union Medical College Hospital is the lead sponsor of 1,148 studies on the registry; 473 are open to participants now.

Of its 5 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 80 Years
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

The study was conducted in renal artery stenosis patients aged 18 to 80 years with uncontrolled blood pressure or impaired renal function, who were intended for endovascular treatment. CTA, MRA, or Doppler ultrasonography were used for the assessment of the stenosis percentage of renal artery. Subjects with technical failure were excluded in order to reduce the influence of other variables.

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • patients who provided informed consent
  • patients who were diagnosed with RAS by CTA, MRA, or Doppler ultrasonography
  • patients who were aged 18 years or older
  • patients whose intervened renal arteries were not completely occluded (confirmed by DSA)
  • the stenosis percentage exceeding 70%
  • patients who had uncontrolled blood pressure or impaired renal function
  • paitents whose affected kidney did not have total loss of function

Exclusion criteria

Exclusion Criteria:

  • were pregnant
  • had a history of renal transplantation or renal artery bypass surgery
  • were allergic to iodine contrast medium
  • had other contraindications of endovascular treatment
  • contraindications of MRI examinations
  • had technical failure in the endovascular treatment.
05

Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
30 participants (estimated)
Patient registry
No

Groups and cohorts

  • Endovascular Group

    Patients who had successful endovascular revascularization

06

What researchers measure

Primary outcomes

  1. Perfusion of the target kidney assessed by Arterial Spin Labelling MRI

    Time frame: Changes from baseline renal perfusion at 2 months

  2. Perfusion of the target kidney assessed by Flat-panel Detector Parenchymal Blood Volume Imaging

    Time frame: Changes from baseline renal perfusion immediately after endovascular intervention

Secondary outcomes

  1. Blood pressure

    Time frame: Changes from baseline blood pressure at 1 year

  2. Renal function

    Time frame: Changes from baseline renal function at 1 year

07

Study locations

1 of 1 sites recruiting
  • Peking Union Medical College Hospital
    Beijing, 100730, China
    Recruiting
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Nov 2, 2022, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT05603221
Responsible party
Sponsor
First posted
Nov 2, 2022
Start date
Nov 4, 2020
Primary completion
Jun 30, 2024 (estimated)
Completion
Jun 30, 2024 (estimated)
Last update
Nov 2, 2022

Study contacts

Bao Liu
Contact
liubao72@aliyun.com
010-69152592

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Oct 2022. You cannot join it, but the record below documents what was studied.

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Sign in to follow

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Start the discussion