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CompletedNCT05589350Updated Apr 18, 2023

High-fat Yogurt and Plasma Lipids Profile

An interventional study of saturated fat intake in Plasma Lipid Profile, sponsored by Shahid Beheshti University. Completed at 1 site in Iran, Islamic Republic of. Open to participants aged 20 Years to 65 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2023-04-18.

Sponsored by Shahid Beheshti University · Not applicable, Interventional, and Prevention

Phase
Not applicable
Study type
Interventional
Enrollment
30
Allocation
Randomized
Ages
20 Years to 65 Years
Sex
All
01

Study summary

The goal of this clinical trial is to compare the effect of saturated fat intake from different source on cardiometabolic risk markers in healthy subjects. The main question it aims to answer are:

-Does intake of saturated fat in the form of high-fat yogurt have a different effect on cardiometabolic risk factors than intake of the same amount from butter? In this study, in two periods of 4 weeks, the effect of receiving saturated fat from high-fat yogurt compared to receiving the same amount of saturated fat from butter and low-fat yogurt on the plasma concentration of lipids, cholesterol, insulin, and some inflammatory factors will be studied in healthy subjects.

02

Conditions studied

  • Plasma Lipid Profile
03

In context

Lead sponsor

Shahid Beheshti University is the lead sponsor of 37 studies on the registry; 3 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
20 Years to 65 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Healthy people who do not use lipid-lowering, blood pressure control or diabetes medications

Exclusion criteria

Exclusion Criteria:

  • Taking supplements of omega-3 fatty acids, or antioxidants
05

Study design

Phase
Not applicable
Primary purpose
Prevention
Allocation
Randomized
Intervention model
Crossover assignment
Masking
Single (Outcomes assessor)
Enrollment
30 participants (actual)

Study arms

  • Experimental
    High-fat yogurt

    Daily consumption of 1-2 servings (based on daily calorie requirement) of high-fat yogurt

    Other: saturated fat intake

  • Active comparator
    Low-fat yogurt and butter

    Daily consumption of 1-2 servings of low-fat yogurt along with daily consumption of about 10 grams of animal butter

    Other: saturated fat intake

Interventions

  • Othersaturated fat intake

    Intake of saturated fat from yogurt and animal butter daily for 4-week period

06

What researchers measure

Primary outcomes

  1. Plasma lipid profile

    Plasma concentrations of cholesterol, high-density lipoprotein cholesterol, Low-density lipoprotein cholesterol, and triglyceride

    Time frame: 4 weeks

Secondary outcomes

  1. Glycemic measures

    Fasting plasma concentrations of glucose and insulin

    Time frame: 4 weeks

Other outcomes

  1. Inflammatory markers

    Plasma concentrations of c-reactive protein and interleukin 6

    Time frame: 4 weeks

07

Study locations

1 site
  • Clinical Nutrition Research Unit, National Nutrition and Food Technology Research Institute
    Tehran, 19395-4741, Iran, Islamic Republic of
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Apr 18, 2023, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT05589350
Lead sponsor
Shahid Beheshti University
Responsible party
Javad Nasrollahzadeh (Associate Professor, Shahid Beheshti University) — Principal investigator
First posted
Oct 21, 2022
Start date
Oct 15, 2022
Primary completion
Apr 13, 2023
Completion
Apr 13, 2023
Last update
Apr 18, 2023

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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This study is completed, as verified in Apr 2023. You cannot join it, but the record below documents what was studied.

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