An observational study in Metabolic Syndrome, sponsored by McGill University Health Centre/Research Institute of the McGill University Health Centre. Recruiting at 1 site in Canada. Open to participants aged 18 Years to 80 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2024-10-24.
Sponsored by McGill University Health Centre/Research Institute of the McGill University Health Centre · Observational
The purpose of this study is to use MRI images using the OS-CMR technique to view the differences in the hearts of healthy volunteers and participants with a condition called Metabolic Syndrome. The objectives of this project are to compare these two groups and to view how health risks, blood test results, and the time since a Metabolic diagnosis can affect heart health.
Myocardial oxygenation changes during vasoactive breathing maneuvers, observed with oxygenation-sensitive cardiac MRI, will be identified and compared between individuals considered healthy and those fitting the criteria of the Metabolic Syndrome.
2,011 studies on the registry are indexed under Metabolic Syndrome; 334 are open to participants now.
This study's planned enrollment of 75 is below the median of 200 across 469 observational studies indexed under Metabolic Syndrome.
Browse Metabolic Syndrome studies →McGill University Health Centre/Research Institute of the McGill University Health Centre is the lead sponsor of 420 studies on the registry; 106 are open to participants now.
Counted across the registry records on this site, refreshed daily.
The study population will be composed of participants with known MetS, based on the identified risk factors, and healthy volunteers.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Patient Participants:
Healthy Volunteers:
Exclusion Criteria:
Participants with known Metabolic Syndrome (MetS)
Diagnostic Test: Cardiac MRI
NonS-moking participants with no known pre-existing conditions and who do not take any medications
Diagnostic Test: Cardiac MRI
Participants will undergo an oxygenation-sensitive cardiac MRI and, during the scan, perform a vasoactive breathing maneuver composed of a period of paced hyperventilation followed by a voluntary maximal breath hold.
Also known as: Breathing Maneuvers
Global and segmental Myocardial oxygenation reserve (MORE)
A t-test will be used to assess the difference in global and segmental MORE, at rest, during hyperventilation, and throughout breath hold, between healthy and volunteers and MetS patients.
Time frame: Baseline
Relation between Breathing maneuver induced MORE and known MetS risk factors.
A linear regression will assess the relation between Breathing maneuver induced MORE and known MetS risk factors, biomarkers, and time since diagnosis.
Time frame: Baseline
Plan to share: No
No publications or documents are linked to this record.
Started Jun 2021 (actual). Primary completion is estimated for Dec 2024, 42 months after the start.
Of 141 non-industry observational studies under Metabolic Syndrome, half reached primary completion within 46 months of starting (the median), counting those still running; a quarter within 18 and three quarters within 106. This study's planned 42 months is close to that.
Counting every sponsor, half of 152 studies reached it within 46 months; a quarter within 18 and three quarters within 106.
How these figures are worked out, and which studies are left out of them.
Eligibility is decided by the study team. Share this record with your doctor or contact the team directly.
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McGill University Health Centre/Research Institute of the McGill University Health Centre →