An observational study in Idiopathic Generalized Epilepsy, sponsored by University Hospital, Lille. Terminated at 1 site in France. Open to participants aged 18 Years to 65 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2025-05-15.
Sponsored by University Hospital, Lille · Observational
Attentional disorders have been reported in neuropsychological studies evaluating patients suffering from generalized idiopathic epilepsy, but the data are disparate (in terms of test protocol). We aim to describe attentional and executive function disorder in IGE thanks to the Epitrack scale, validated in this specific population. Our secondary objective is to study the dynamic of cortical activity during an attentional task (the ANT), in order to describe the alteration of cortical networks in epileptic patients presenting with attentional disturbance.
35 studies on the registry are indexed under Epilepsy, Idiopathic Generalized; 4 are open to participants now.
Browse Epilepsy, Idiopathic Generalized studies →University Hospital, Lille is the lead sponsor of 631 studies on the registry; 142 are open to participants now.
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patients from the clinical neurophysiology department of the Lille University Hospital, a reference centre for the follow-up of rare epilepsies.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Short tests of memory and thinking, each scored out of 30. Lower scores suggest more difficulty; criteria give a range, either to include people with memory problems or to leave them out.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
MMSE and MoCA
Short tests of memory and thinking, each scored out of 30. Lower scores suggest more difficulty; criteria give a range, either to include people with memory problems or to leave them out.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Other: Neuropsychological screening and high resolution EEG recording
age- and sex-matched healthy controls
Other: Neuropsychological screening and high resolution EEG recording
Each participant will be assessed with a battery of neuropsychological tests including Epitrack, the Raven's progressive matrice, the MoCA, the D2-R test, the BDI-II test, the STAI and the Qolie-31. Then, a prolonged EEG recording at rest and during an attentional task (the ANT) will be realized
Epitrack scale score
EPITrack-Score shows the performance of attention and executive functions. Higher values indicate a better performance. scale from 9-49 (9 worst score - 49 best score)
Time frame: At 1 month after inclusion
Raven's progressive matrice scores
cortical source connectivity patterns.
Time frame: At 1 month after inclusion
Montreal Cognitive Assessment (MoCA) score
Cognitive function was assessed by using MoCA score. Cognitive impairment was considered present when MoCA scores were \<26 .
Time frame: At 1 month after inclusion
D2-R test score
cortical source connectivity patterns.
Time frame: At 1 month after inclusion
BDI-II score
Anxiety-depressive symptoms score Beck Depressive Inventory Questionnaire (BDI-II) (score), higher scores mean worse outcome, value minimum of 0 maximum 63
Time frame: At 1 month after inclusion
STAI scale
Anxiety-depressive symptoms score The State-Trait Anxiety Inventory (STAI) is a self-questionnaire, 20 questions, a score is calculated, ranging from 20 to 80, a high score indicating the presence of anxiety.
Time frame: At 1 month after inclusion
quality of life using the Qolie-31 self questionnaire
Quality Of Life In Epilepsy-Problems questionnaire (QOLIE31-P) questionnaire has been developed specifically to measure the quality of life of patients with epilepsy. The score ranges from 0 to 100 points. Higher scores reflect better quality of life; lower ones, worse quality of life.
Time frame: At 1 month after inclusion
High resolution Electro Encephalo Gram functional connectivity markers at rest and during the ANT task
limited number of reproducible resting activity patterns, brain networks involved in the absence of task performance
Time frame: At 1 month after inclusion
Ran from Apr 2022 to primary completion in Apr 2025, 35 months.
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This study is terminated, as verified in May 2025. You cannot join it, but the record below documents what was studied.
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